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| Clinical observation of Guizhi plus Huangqi Decoction combined acupuncture treatment of allergic rhinitis lung qi deficiency cold syndrome |
| Hits 199 Download times 113 Received:October 10, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2024.03.14 |
| Key Words
Guizhi plus Huangqi Decoction;acupuncture;allergic rhinitis;inflammation;nasal mucociliary function |
| Author Name | Affiliation | | YANG Fei | Department of Untreated Diseases, Jiamusi Hospital of Traditional Chinese Medicine, Jiamusi 154002, China | | LI Peng | Department of Untreated Diseases, Jiamusi Hospital of Traditional Chinese Medicine, Jiamusi 154002, China | | WU Bentao | Department of Untreated Diseases, Jiamusi Hospital of Traditional Chinese Medicine, Jiamusi 154002, China | | ZHANG Qiang | Department of Untreated Diseases, Jiamusi Hospital of Traditional Chinese Medicine, Jiamusi 154002, China | | WANG Dongmin | Department of Untreated Diseases, Jiamusi Hospital of Traditional Chinese Medicine, Jiamusi 154002, China | | ZENG Xiangrui | Department of Untreated Diseases, Jiamusi Hospital of Traditional Chinese Medicine, Jiamusi 154002, China |
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| Abstract
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| [Objective] To observe the clinical effect of Guizhi plus Huangqi Decoction combined acupuncture on allergic rhinitis syndrome of lung qi deficiency and cold. [Methods] The 80 patients with allergic rhinitis were selected and divided into Western medicine group and Chinese medicine group according to random number table,40 cases in each group. The Western medicine group was given conventional Western medicine treatment,and the Chinese medicine group was given Guizhi plus Huangqi Decoction and acupuncture treatment on the basis of the Western medicine group. The expression levels of serum aquaporin 1 (AQP1),atopic immunoglobulin E(IgE),nuclear transcription factor-κB(NF-κB) and n-pentammer protein 3(PTX3) in the two groups were observed before and after treatment. Eosinophils(EOS) of nasal secretions were detected,and allergic rhinitis symptom score(TNSS+TNNSS) and nasoconjunctivitis Quality of Life Scale(RQLQ) were evaluated between the two groups,and the clinical efficacy was compared between the two groups. [Results] After treatment,the contents of EOS and IgE in Chinese medicine group were lower than those in Western group,and the difference was statistically significant(P<0.05). After treatment,the contents of AQP1,NF-κB and PTX3 in Chinese medicine group were significantly lower than those in Western group,and the difference was statistically significant(P<0.05). After treatment,the clearance rate of nasal mucosa cilia in the Chinese medicine group was higher than that in the Western group,the nasal resistance was lower,and the transmission time of nasal mucosa cilia was shorter than that in the Western group,with statistical significance(P<0.05). After treatment,symptom score of allergic rhinitis(TNSS+TNNSS) in Chinese medicine group was lower than that in Western group,and the difference was statistically significant(P<0.05). After treatment,RQLQ score in Chinese medicine group was lower than that in Western group,and the difference was statistically significant(P<0.05). After treatment,the total effective rate was 97.50% in the Chinese medicine group and 80.00% in the Western medicine group,and the difference was statistically significant(P<0.05). [Conclusion] Guizhi plus Huangqi Decoction combined acupuncture in the treatment of allergic rhinitis patients with lung qi deficiency and cold syndrome can reduce EOS and IgE levels,inhibit body inflammation,improve nasal ventilation and nasal mucociliary function, relieve clinical symptoms,reduce RQLQ score,and improve clinical efficacy of patients. |
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