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Research progress on pharmacological effects and clinical applications of mineral Chinese medicine in the treatment of insomnia
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DOI   10.11656/j.issn.1672-1519.2024.03.22
Key Words   mineral Chinese medicine;insomnia;pharmacological mechanism;clinical application;research progress
Author NameAffiliationE-mail
CHAI Shiwei First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China  
FAN Baishuang First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China  
SONG Xuejiao Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
ZHUANG Pengwei Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China zhuangpengwei@163.com 
Abstract
    Mineral Chinese medicine plays the mind-tranquilizing role in treating insomnia. Through searching relevant works and literature,there are 16 kinds of mineral Chinese medicine for insomnia,which are commonly used in clinical treatment of chronic insomnia caused by various forms such as perimenopausal insomnia,diabetes related insomnia,depressive insomnia,intractable insomnia,etc. They mainly exert therapeutic effects by regulating the abnormal expression of neurotransmitters,reducing the release of inflammatory factors and oxidative stress factors,downregulating the secretion of hypothalamus pituitary adrenal (HPA) axis hormones, prolonging slow wave and rapid eye movement sleep periods. This article reviews the pharmacological research and clinical application progress of mineral Chinese medicine,in order to provide reference for the development and utilization in the treatment of insomnia.

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