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Research progress in the potential mechanism of Chinese medicine in the treatment of functional constipation
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DOI   10.11656/j.issn.1672-1519.2024.09.22
Key Words   Chinese medicine;functional constipation;mechanism of action
Author NameAffiliationE-mail
ZHANG Yawei Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
DONG Yang Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
PAN Lihong State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co Ltd Linyi 276006, China  
CHEN Qian Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
WANG Dan Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 
 
LIU Mengyang Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 
 
WU Yuzheng Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 
wyz2019@tjutcm.edu.cn 
WANG Tao Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 
 
Abstract
    Functional constipation is the most common type of chronic constipation,which belongs to chronic functional intestinal diseases,characterized by recurrent episodes and difficult to be cured. Although short-term constipation is not life-threatening,gastrointestinal discomfort caused by constipation seriously affects patients’ quality of life,and long-term constipation may increase the incidence of colorectal tumors. Traditional Chinese medicine has obvious advantages in enhancing gastrointestinal motility and regulating intestinal peristalsis rhythm. This article summarizes the research progress of the application and mechanism research of traditional Chinese medicine in the treatment of functional constipation in recent years,provides reference for further research on the efficacy and mechanism of traditional Chinese medicine in the treatment of functional constipation.

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