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Analysis of clinical characteristics of Chinese medicine evidence in elderly patients with type 2 diabetes mellitus combined with sarcopenia
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DOI   10.11656/j.issn.1672-1519.2024.10.03
Key Words   type 2 diabetes mellitus;sarcopenia;TCM syndrome element
Author NameAffiliationE-mail
XIAO Yanyan Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
XU Jiahui Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
TIAN Jing Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
CHEN Yuan Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
ZHOU Tiankai Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
WANG Chao Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
CHEN Chi Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
HAN Xu Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
CHEN Qingguang Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China  
ZHAO Jindong Department of Endocrinology, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230031, China  
XU Junfei Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China junfei.xu@shsgyy-endo.cn 
LU Hao Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China luhao403@163.com 
Abstract
    [Objective] To analyze the distribution pattern and combination characteristics of traditional Chinese medicine(TCM) evidence elements in elderly patients with type 2 diabetes mellitus combined with sarcopenia,and to provide an objective and scientific reference basis for TCM treatment based on pattern identification. [Methods] Through a cross-sectional survey,the four diagnostic methods and related information of 200 elderly patients with type 2 diabetes mellitus combined with sarcopenia were collected to analyze the general conditions of the target patients,and the distribution characteristics of the evidence elements and patterns of the disease and the combination pattern of the feet were obtained by adopting the method of evidence element identification and using statistical methods such as frequency counting,R-type cluster analysis,and based on the theory of evidence element identification. [Results] The ratio of male to female patients is about 5∶2,and there were significantly more male patients than female patients. Elderly patients with type 2 diabetes mellitus combined with sarcopenia were mainly concentrated in the group with normal BMI. The pathogenic elements of type 2 diabetes mellitus combined with sarcopenia in the elderly were mainly liver(44.5%),kidney(41.0%),and spleen(18.0%),and the pathogenic elements were blood deficiency(80.1%),yin deficiency(64.0%),qi deficiency(48.5%),and yang deficiency(43.5%),and the deficiency elements were mainly,and the blood deficiency was especially common. Cluster analysis clustered the symptoms into three types:liver yin and blood deficiency(67.0%),kidney yang and qi deficiency(26.0%),and spleen-stomach phlegm-dampness and qi stagnation and blood stasis(7.0%). [Conclusion] Type 2 diabetes mellitus combined with sarcopenia in the elderly population focuses on the liver,which is closely related to the kidney and spleen,and focuses on blood deficiency,which is closely related to yin,qi,and yang deficiencies. The clinical evidence pays attention to the characteristics of the elderly,the identification of the disease locus focuses on the liver,spleen,and kidney,and the focus is on supplementing the deficiency,especially on supplementing the blood. The results of this study reflect some extent the characteristics of the main evidence of type 2 diabetes mellitus with sarcopenia in the elderly,and it has a certain value of reference for the treatment of this disease in clinical Chinese medicine identification and treatment.

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