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| Clinical observation on acupuncture combined with antiemetic drugs in the treatment of chemotherapy-induced nausea and vomiting in gastric cancer patients |
| Hits 650 Download times 236 Received:April 23, 2024 |
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| DOI
10.11656/j.issn.1672-1519.2024.10.05 |
| Key Words
gastric cancer;chemotherapy-induced nausea and vomiting;acupuncture;antiemetic drug;curative effect |
| Author Name | Affiliation | E-mail | | LIU Honggen | Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | ZHAO Linlin | Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | YANG Peiying | Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | KONG Fanming | Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | JIA Yingjie | Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | jiayingjie1616@sina.com |
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| Abstract
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| [Objective] This study aimed to explore the effectiveness of acupuncture in treatment of chemotherapy-induced nausea and vomiting(CINV) among advanced cancer patients receiving chemotherapy. [Methods] Gastric cancer patients who were hospitalized from January 2022 to December 2023 were collected. According to whether it was acupuncture treatment during chemotherapy,all patients were divided into the antiemetic drugs group and the acupuncture with antiemetic drugs group. The observational indexes were the incidence of acute nausea and vomiting and delayed nausea and vomiting,the total number of nausea and vomiting during chemotherapy,quality of life,safety,and antiemetic drug-related adverse reactions. [Results] Compared with the antiemetic drugs group,the acupuncture with antiemetic drugs group can reduce acute and delayed CINV(P<0.05),and the frequency of nausea and vomiting were decreased in this group(P<0.05). The ECOG-KPS score in the the acupuncture with antiemetic drugs group was significantly improved(P=0.028). Acupuncture had higher safety. In addition,the adverse events of antiemetic drugs,such as constipation(P=0.031) and diarrhea(P=0.005),were decreased by acupuncture. [Conclusion] Acupuncture combined with antiemetics could reduce the incidence of CINV,improve the quality of life of patients,and reduce the incidence of adverse side effects of antiemetic drugs. |
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