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Exploring myocardial energy metabolism in heart failure and the mechanism of Chinese medicine intervention based on the “theory of antipathogenic qi and pathogenic factors”
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DOI   10.11656/j.issn.1672-1519.2024.10.19
Key Words   heart failure;theory of antipathogenic qi and pathogenic factors;myocardial energy metabolism;Chinese medicine intervention
Author NameAffiliationE-mail
YUAN Hui The First Clinical College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha 410208, China
Hunan Provincial Key Laboratory of Intelligent Diagnosis of Chronic Diseases by Traditional Chinese Medicine and Treatment of Future Diseases, Hunan University of Chinese Medicine, Changsha 410208, China
Postgraduate Joint Training Base of Internet+TCM Diagnosis and Treatment of Chronic Diseases and Intelligent Application of Health Care, Changsha 410208, China 
 
WEI Jiaming The First Clinical College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha 410208, China
Hunan Provincial Key Laboratory of Intelligent Diagnosis of Chronic Diseases by Traditional Chinese Medicine and Treatment of Future Diseases, Hunan University of Chinese Medicine, Changsha 410208, China
Postgraduate Joint Training Base of Internet+TCM Diagnosis and Treatment of Chronic Diseases and Intelligent Application of Health Care, Changsha 410208, China 
 
SHI Min The First Clinical College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha 410208, China
Hunan Provincial Key Laboratory of Intelligent Diagnosis of Chronic Diseases by Traditional Chinese Medicine and Treatment of Future Diseases, Hunan University of Chinese Medicine, Changsha 410208, China
Postgraduate Joint Training Base of Internet+TCM Diagnosis and Treatment of Chronic Diseases and Intelligent Application of Health Care, Changsha 410208, China 
 
GUO Zhihua The First Clinical College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha 410208, China
Hunan Provincial Key Laboratory of Intelligent Diagnosis of Chronic Diseases by Traditional Chinese Medicine and Treatment of Future Diseases, Hunan University of Chinese Medicine, Changsha 410208, China
Postgraduate Joint Training Base of Internet+TCM Diagnosis and Treatment of Chronic Diseases and Intelligent Application of Health Care, Changsha 410208, China 
guozhihua112@163.com 
Abstract
    Myocardial energy metabolism disorder is an important feature of heart failure,improving myocardial energy metabolism has become a crucial means of prevention and treatment of heart failure. Traditional Chinese medicine has shown unique advantages in terms of improving myocardial energy metabolism by virtue of its concept of syndrome differentiation and multi-target comprehensive regulation. The occurrence and development of heart failure stem from the struggle between antipathogenic qi and pathogenic factors and the syndrome type of heart failure is healthy qi deficiency and pathogenic qi excess. Dysfunction of myocardial energy metabolism can be regarded microscopically as a manifestation of healthy qi deficiency. Therefore,based on the “theory of antipathogenic qi and pathogenic factors” and the basic principle of “reinforce healthy qi to eliminate pathogenic factors”,it’s of great significance for treating heart failure determining methods and selecting prescriptions to improve myocardial energy metabolism.

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