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| Discussion on syndrome differentiation factors of lower extremity atherosclerosis disease with qi deficiency and phlegm stasis syndrome based on set pair analysis |
| Hits 55 Download times 10 Received:August 15, 2024 |
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| DOI
10.11656/j.issn.1672-1519.2025.02.03 |
| Key Words
set pair analysis;lower extremity atherosclerosis disease;qi deficiency and phlegm stasis syndrome;syndrome differentiation factor;partial connection coefficient |
| Author Name | Affiliation | E-mail | | WANG Zhaozheng | Department of Geriatrics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | | CHEN Xianchuan | Department of Geriatrics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | | QIAN Fenghua | Department of Geriatrics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | | JIANG Kai | Department of Geriatrics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | | PU Yuling | Department of Geriatrics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | | ZHANG Jiawei | Department of Geriatrics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | | SHEN Rong | Department of Geriatrics, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | rrrooonnnggg@126.com |
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| Abstract
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| [Objective] To preliminarily identify the associated factors of traditional Chinese medicine（TCM） syndrome differentiation of qi deficiency and phlegm stasis in lower extremity atherosclerosis disease（LEAD），to enhance the precision of clinical syndrome differentiation for this condition. [Methods] The general condition，symptoms，signs，and auxiliary examination results of 500 patients diagnosed with qi deficiency and phlegm stasis syndrome of LEAD were summarized. Based on the set pair analysis method，the factors associated with TCM syndrome differentiation of qi deficiency and phlegm stasis syndrome of LEAD were screened and sorted according to the connection number. [Results] According to the potential function，the main factors affecting the qi deficiency and phlegm stasis syndrome in patients with and without LEAD were “phlegm ≥1 point” and “ABI <0.9”，while the medium factors were “head weight such as coating ≥1 point”“diabetes history”“smoking history”“white or yellow greasy fur ≥2 points”“pale or yellow complexion ≥2 points”“male gender”“lip color purple and dark≥1 point”“history of hypertension”“spirit fatigue ≥2 points”“chest tightness ≥2 points”“palpitation ≥1 point”“age ≥60 years old”，and the rest were considered minor factors. To study the TCM syndrome differentiation of LEAD with qi deficiency and phlegm stasis syndrome，it was found that “pale or dark tongue，or petechiae，or tooth marks” “spiritual fatigue” “smooth or astringent pulse string，knot，or weak” “white or yellow greasy fur” “pale or yellow complexion” were the main TCM syndrome differentiation factors. Based on the three-order partial connection number of the four-element connection number，it was found that the six differentiation factors of “dizziness” “spiritual fatigue” “phlegm” “lip color purple and dark” “smooth or astringent pulse string，knot，or weak” “white or yellow greasy fur” showed a potential development trend towards heavier degrees of severity，while the other differentiation factors tended to be milder. [Conclusion] The main and minor syndrome differentiation factors of qi deficiency phlegm stasis syndrome of LEAD，screened and sorted by the set pair analysis method，were in line with clinical practice，which is conducive to the construction of syndrome differentiation model of LEAD and help to realize the objectification of TCM syndrome differentiation，thus improving the accuracy of clinical syndrome differentiation，and at the same time，it is beneficial to early clinical intervention of some risk factors and syndrome differentiation factors，to improve clinical therapeutic efficacy. |
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