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| Effect of Guasha combined with blood-letting puncture plus cupping therapy on symptoms and future risk of patients with stable COPD |
| Hits 63 Download times 7 Received:September 25, 2024 |
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| DOI
10.11656/j.issn.1672-1519.2025.03.04 |
| Key Words
Guasha;blood-letting puncture plus cupping;COPD;single blind;RCT |
| Author Name | Affiliation | E-mail | | ZHANG Hong | Rehabilitation Department, Tianjin Haihe Hospital, Tianjin 300350, China
Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | | | SU Jingshen | Pulmonary Medicine Department, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | MA Zhaorun | Rehabilitation Department, Tianjin Haihe Hospital, Tianjin 300350, China
Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | | | LIU Chenchao | Rehabilitation Department, Tianjin Haihe Hospital, Tianjin 300350, China
Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | | | FENG Liting | Rehabilitation Department, Tianjin Haihe Hospital, Tianjin 300350, China
Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | | | ZHANG Fengchao | Rehabilitation Department, Tianjin Haihe Hospital, Tianjin 300350, China
Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | | | CHEN Ruixue | Rehabilitation Department, Tianjin Haihe Hospital, Tianjin 300350, China
Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | | | SU Dongyue | Rehabilitation Department, Tianjin Haihe Hospital, Tianjin 300350, China
Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | focuslrm@126.com |
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| Abstract
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| [Objective] To evaluate the effect of Guasha combined with blood-letting puncture plus cupping therapy on symptoms and future risk of stable COPD patients. [Methods] A total of 120 patients with stable COPD recruited from December 1，2021 to December 31，2023 were randomly divided into the Guasha combined with blood-letting puncture plus cupping group，the Guasha group and the control group with 40 cases each. The Guasha combined with blood-letting puncture plus cupping therapy was applied to the test group，the single Guasha therapy was applied to the Guasha group，and sham Guasha was applied to the control group. The whole treatment period consisted of 2 courses（the Dog Days and the Coldest Days of Winter），including eight times of Guasha（sham Guasha） treatment and twenty-four times of blood-letting puncture plus cupping treatment for all courses. The follow-up period was 6 months. Before and after treatment and during follow-up，pulmonary function（PFT） indexes were recorded，including forced first second expiratory volume（FEV1%） and FEV1/FVC%（ratio of forced expiratory volume in one second to forced vital capacity），arterial partial pressure of oxygen（PaO2） and arterial partial pressure of carbon dioxide（PaCO2），St. George’s Respiratory Questionnaire（SGRQ），6-minute walk test distance（6MWD），and the number of acute exacerbations. The changes of indexes before and after treatment and during follow-up were evaluated. [Results] During the study，the PET，PaO2 and SGRQ scores of both Guasha combined with blood-letting puncture plus cupping group and Guasha group increased，and repeated measurement ANOVA at three time points before treatment，after treatment and during follow-up showed that the time of the above indicators and the interaction between the groups were statistically significant（P＜0.05）. Intra-group comparison showed that the PET，PaO2 index and SGRQ scores of the Guasha combined with blood-letting puncture plus cupping group and Guasha group after treatment and during follow-up were higher than those before treatment（P＜0.05）. Comparison between groups showed that there were no differences in PET index and SGRQ score between Guasha combined with blood-letting puncture plus cupping group and Guasha group after treatment and during follow-up（P>0.05），but there were differences in PaO2 after treatment and during follow-up（P＜0.05），and both were higher than those in control group（P＜0.05）. However，repeated measurement ANOVA of PaCO2 in the three groups showed no statistical significance in the interaction between time and groups（P>0.05），and there were no differences in intra-group and inter-group comparisons（P>0.05）. [Conclusion] Both the Guasha combined with blood-letting puncture plus cupping and the single Guasha can effectively improve the airflow limitation of stable COPD，the arterial oxygen content，the cardiopulmonary endurance，improve the quality of life，reduce the number of acute aggravation events，and have a post-treatment effect. Basically，the two therapies have the same effects in improving airflow limitation，improving cardiorespiratory endurance，and reducing the risk of future exacerbations. And neither therapy could improve the state of CO2 retention. However，the Guasha combined with blood-letting puncture plus cupping can significantly improve blood oxygen content better than Guasha alone. |
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