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The application of toxic Chinese medicine in the Book of Huoyou Xinshu
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DOI   10.11656/j.issn.1672-1519.2025.04.11
Key Words   toxic Chinese medicine;Huoyou Xinshu;using toxicity;preventing toxicity
Author NameAffiliationE-mail
REN Xiaodan Pediatric Department, the First Affiliated Hospital of Henan University of Chinese medicine, Zhengzhou 450001, China
School of Pediatrics, Henan University of Chinese Medicine, Zhengzhou 450046, China 
 
DING Ying Pediatric Department, the First Affiliated Hospital of Henan University of Chinese medicine, Zhengzhou 450001, China dingying3236@sina.com 
SUN Zhaoheng Pediatric Department, the First Affiliated Hospital of Henan University of Chinese medicine, Zhengzhou 450001, China
School of Pediatrics, Henan University of Chinese Medicine, Zhengzhou 450046, China 
 
XU Shanshan Pediatric Department, the First Affiliated Hospital of Henan University of Chinese medicine, Zhengzhou 450001, China  
HAN Shanshan Pediatric Department, the First Affiliated Hospital of Henan University of Chinese medicine, Zhengzhou 450001, China  
XING Yaping Pediatric Department, the First Affiliated Hospital of Henan University of Chinese medicine, Zhengzhou 450001, China
School of Pediatrics, Henan University of Chinese Medicine, Zhengzhou 450046, China 
 
Abstract
    Toxic Chinese medicines are highly specialized and effective in treating certain conditions. However,their toxic side effects often limit their widespread clinical application. Children,with their delicate internal organs that are not yet fully developed in form and qi,are particularly susceptible to the harmful effects of these toxic substances. The book Huoyou Xinshu focuses on the academic thoughts of ZENG Shirong,a renowned pediatrician,and its exploration of toxic Chinese medicines holds significant academic value. This article reviews the methods of using and preventing toxicity described in Huoyou Xinshu. It elucidates the principles of using toxic medicines by discussing the identification of deficiency and excess,appropriate attack and supplementation,precise symptom-based medication,accurate dosage adjustment,cautious administration,prompt cessation of treatment,and attention to post-treatment care. Additionally,it explains the strategies for preventing and reducing toxicity through rational formulations,diverse dosage forms,the use of auxiliary agents to facilitate drug delivery,and timely administration of medicine. This study aims to provide a reference for the safe and effective application of toxic traditional Chinese medicines in pediatric practice.

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