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Historical evolution and modern research progress of Zixue Powder
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DOI   10.11656/j.issn.1672-1519.2025.06.19
Key Words   Zixue Powder;historical evolution;chemical composition;clinical application;quality analysis;development and utilization
Author NameAffiliationE-mail
ZOU Lin State Key Laboratory of Component-based Chinese Medicine, State Key Laboratory of Chinese Medicine Modernization, National Inheritance Studio of Expert Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
SONG Lingling State Key Laboratory of Component-based Chinese Medicine, State Key Laboratory of Chinese Medicine Modernization, National Inheritance Studio of Expert Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
CHAI Xin State Key Laboratory of Component-based Chinese Medicine, State Key Laboratory of Chinese Medicine Modernization, National Inheritance Studio of Expert Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China 
 
WANG Yuefei State Key Laboratory of Component-based Chinese Medicine, State Key Laboratory of Chinese Medicine Modernization, National Inheritance Studio of Expert Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China 
 
CUI Ying State Key Laboratory of Component-based Chinese Medicine, State Key Laboratory of Chinese Medicine Modernization, National Inheritance Studio of Expert Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China 
CQL8179270@tjutcm.edu.cn 
Abstract
    Zixue Powder,derived from the “Zixue” in “Qianjin Yifang”,is the representative prescription in the cold formulas for resuscitation. Zixue Powder,Angong Niuhuang Pill and Zhibao Bolus are collectively known as “three treasures for seasonal febrile disease”. Zixue Powder has a variety of ingredients,and has shown a variety of pharmacological effects,such as febrifuge,sedation,anti-inflammation,anticonvulsant,etc.,which has been widely used in the treatment of children with febrile convulsion,septic shock and other diseases. In this paper,the historical development,chemical components,modern clinical application,pharmacological action,preparation technology,quality control,development and utilization of Zixue Powder were reviewed,in order to provide some reference for the rational research and utilization of this classic prescription.

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