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| Experience of national traditional Chinese medicine Master ZHANG Zhen in treating depression with three-herb combinations（Jiaoyao） |
| Hits 458 Download times 108 Received:July 10, 2025 |
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| DOI
10.11656/j.issn.1672-1519.2025.12.01 |
| Key Words
depression;three-herb combinations;regulating qi movement;ZHANG Zhen;experience of famous doctors |
| Author Name | Affiliation | E-mail | | ZHOU Ming | Yunnan University of Traditional Chinese Medicine, Kunming 650500, China | | | ZHU Jianping | Puer Hospital of Traditional Chinese Medicine, Puer 665000, China | | | SONG Zhicheng | Yunnan University of Traditional Chinese Medicine, Kunming 650500, China | | | XU Yun | Yunnan University of Traditional Chinese Medicine, Kunming 650500, China | | | TIAN Yuan | Yunnan Institute of Traditional Chinese Medicine, Kunming 650223, China | | | TIAN Chunhong | Yunnan Institute of Traditional Chinese Medicine, Kunming 650223, China | Tch9001@163.com |
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| Abstract
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| Summarizing national traditional Chinese medicine Master ZHANG Zhen’s experience in treating depression with three-herb combinations（Jiaoyao）. Depression，a prevalent mental disorder，significantly impacts patients’ daily lives and productivity. Three-herb combinations，composed of three mutually complementary herbs，synergistically enhance therapeutic efficacy，modulate herb properties，and mitigate toxicity. Master ZHANG posits that the core pathogenesis of depression lies in liver qi stagnation and dysregulation of qi movement. Thus，treatment should prioritize soothing the liver，relieving stagnation，and harmonizing visceral functions. This study analyzes Master ZHANG’s clinical application of six herb triplets for depression：Chaihu-Zhishi-Xiangfu，Meiguihua-Houpohua-Suxinhua，Yuanzhi-Shichangpu-Hehuanpi，Foshou-Qingpi-Zisugeng，Bohe-Gansong-Cijili，Fuling-Fabanxia-Tianzhuhuang. Each combination is examined for its compositional efficacy，compatibility principles，indications，and modifications based on syndrome differentiation. The aim is to analyze Professor ZHANG’s experience and improve the clinical efficacy of traditional Chinese medicine in treating depression. |
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