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| Analysis of the correlation between Chinese medicine constitution and the occurrence of restless legs syndrome in dialysis patients with end-stage renal disease |
| Hits 280 Download times 95 Received:September 04, 2025 |
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| DOI
10.11656/j.issn.1672-1519.2025.12.05 |
| Key Words
end-stage renal disease;restless legs syndrome;constitution;Pittsburgh Sleep Quality Index |
| Author Name | Affiliation | E-mail | | XIAO Xue | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China | | | HAN Yingying | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China | | | XU Chuhan | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China | | | YUAN Tao | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China | | | LI Huanan | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China
Key Laboratory of Tuina Therapy for Biological Effects, State Administration of Traditional Chinese Medicine, Tianjin 300193, China | | | TAN Tao | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China
Key Laboratory of Tuina Therapy for Biological Effects, State Administration of Traditional Chinese Medicine, Tianjin 300193, China | 13072240977@163.com | | CHANG Wenxiu | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China | changwx@sina.com |
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| Abstract
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| [Objective] To investigate the risk factors and constitution distribution characteristics of restless legs syndrome（RLS） in end-stage renal disease（ESRD） patients undergoing hemodialysis and peritoneal dialysis. [Methods] A questionnaire survey was conducted among 194 hemodialysis patients and 242 peritoneal dialysis patients to assess the occurrence of RLS and Pittsburgh Sleep Quality Index（PSQI） scores. Laboratory data were collected，and the constitution of all patients was classified according to the “Classification and determination of traditional Chinese medicine constitution table”. The distribution of traditional Chinese medicine constitutions and risk factors for RLS in ESRD dialysis patients were analyzed. [Results] The primary constitutions among all patients were balanced constitution（23.17%），yin deficiency constitution（23.17%），yang deficiency constitution（19.27%），and phlegm-dampness constitution（16.51%）. Among hemodialysis patients，the most common imbalanced constitution was yin deficiency（25.26%），while among peritoneal dialysis patients，it was also yin deficiency（21.49%）. In patients with RLS，yin deficiency（28.57%） and yang deficiency（23.15%） constitutions were the most prevalent. Multivariate logistic regression analysis revealed that longer dialysis duration，lower hemoglobin levels，and higher blood phosphorus levels were risk factors for RLS in dialysis patients. Compared to patients with a balanced constitution，those with yin deficiency and yang deficiency constitutions were more prone to RLS. The occurrence of RLS was correlated with decreased sleep quality.[Conclusion] ESRD patients undergoing dialysis exhibit specific constitution distribution characteristics. In addition to clinical risk factors，patients with yin deficiency and yang deficiency constitutions are more susceptible to RLS，warranting special attention and regulation in clinical practice. |
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