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| Research progress on treating atherosclerosis by improving endothelial cell dysfunction with traditional Chinese medicine |
| Hits 946 Download times 64 Received:July 01, 2025 |
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| DOI
10.11656/j.issn.1672-1519.2025.12.17 |
| Key Words
endothelial cell dysfunction;atherosclerosis;traditional Chinese medicine |
| Author Name | Affiliation | E-mail | | ZHAO Yuke | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | GUO Haizhen | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LI Xiaofeng | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | WANG Runying | Jiyuan Vocational and Technical College, Jiyuan 459000, China | | | QIAN Shule | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | CONG Zidong | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | DU Wuxun | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | cnduwux@163.com |
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| Abstract
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| Endothelial cell dysfunction（ECD） is a pathological state characterized by impaired barrier function，reduced vasodilation，oxidative stress，as well as a pro-inflammatory and pro-thrombotic status. ECD is regarded as the initiating factor in atherosclerosis（AS）. This review elaborates on the specific mechanisms by which ECD promotes AS and discusses therapeutic strategies using traditional Chinese medicine to ameliorate ECD，aiming to provide new insights for traditional Chinese medicine interventions to delay the progression of AS. |
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