|
| Clinical efficacy of Duhuo Jisheng Decoction combined with Tuina for chronic nonspecific low back pain and its effects on lumbar function and serum IL-1β，IL-6，and TNF-α |
| Hits 610 Download times 206 Received:February 13, 2025 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2025.08.07 |
| Key Words
Duhuo Jisheng Decoction;Tuina;chronic non-specific lower back pain;traditional Chinese medicine syndrome;lower back function |
| Author Name | Affiliation | | HUO Yichao | Department of Traditional Chinese Medicine, Xingtai Central Hospital, Xingtai 054000, China | | ZHAO Weiran | Department of Traditional Chinese Medicine, Xingtai Central Hospital, Xingtai 054000, China | | QI Huanhuan | Department of Functional Examination, Xingtai Central Hospital, Xingtai 054000, China | | ZHAO Ruihao | Department of Orthopedics, Lincheng County People's Hospital, Lincheng 054300, China |
|
| Abstract
|
| [Objective] To investigate the clinical efficacy of Duhuo Jisheng Decoction combined with Tuina in treating chronic non-specific lower back pain（CNLBP），and its impacts on lower back function and serum levels of interleukin-1β（IL-1β），interleukin-6（IL-6），and tumor necrosis factor-α（TNF-α）. [Methods] A total of 126 patients with CNLBP treated in Xingtai Central Hospital were stochastically grouped into a Tuina group and a combination group using a random number table，with 63 cases in each group. The Tuina group was treated with traditional Chinese Tuina techniques，while the combination group was treated with Duhuo Jisheng Decoction combined with Tuina. Two groups were compared in terms of clinical efficacy，traditional Chinese medicine syndrome score，lower back function，serum levels of inflammatory factors（IL-1β，IL-6，TNF-α），and incidence of adverse reactions. [Results] The total effective rate of the combination group was 95.24%，significantly higher than the 76.19% of the Tuina group（P＜0.05）. After treatment，the scores of traditional Chinese medicine syndrome，back flexion/extension ratio（F/E），serum IL-1β，IL-6，and TNF-α levels in both groups decreased，and the combination group was significantly lower than the Tuina group（P＜0.05）. After treatment，peak torque（PT） and the average power under lumbar and back extension（AP） increased，and the combination group was significantly higher than the Tuina group（P＜0.05）. No adverse reactions occurred in either group. [Conclusion] The combination of Duhuo Jisheng Decoction and Tuina can achieve good clinical effects in treating CNLBP，it can effectively alleviate traditional Chinese medicine syndrome，restore their lower back function，effectively inhibit the release of related inflammatory factors，control the development of the disease，and has high safety. |
|
