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| Exploration of therapeutic approaches for advanced-stage essential thrombocythemia on “blood stasis caused by deficiency” |
| Hits 3964 Download times 157 Received:May 03, 2025 |
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| DOI
10.11656/j.issn.1672-1519.2025.09.08 |
| Key Words
essential thrombocythemia;accumulation;blood stasis caused by deficiency;qi and blood;yin and yang |
| Author Name | Affiliation | E-mail | | QIAN Yuxiao | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
Beijing University of Chinese Medicine, Beijing 100029, China | | | HUANG Xiaohua | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | SHI Ying | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | MA Wei | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | LANG Haiyan | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | julietlang@126.com |
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| Abstract
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| Essential thrombocytosis（ET） is a myeloproliferative tumor characterized by increased platelet count in peripheral blood. The main clinical manifestations are thrombosis and bleeding tendency. Western medicine treatment is mainly based on thrombosis prevention and platelet lowering treatment according to risk stratification. Its side effects are large，and there are many adverse reactions，which seriously affect the quality of life of patients. In the early stage of essential thrombocythemia，exogenous and internal injuries caused the accumulation of pathogenic factors in the body，the struggle between healthy qi and pathogenic factors，and the excess as the main. With the progress of the disease，it is attacked by the excess and pathogenic factors. Over time，it is easy to make qi，blood，yin and yang deficiency，deficiency can cause blood stasis. Based on the clinical observation and the summary of the experience of famous old Chinese medicine doctors in the diagnosis and treatment of ET，the author and the team of our department put forward the theory of “blood stasis caused by deficiency” in the later stage of ET disease，and believed that the cause of ET is the lack of congenital endowment，acquired dystrophy，combined with the attack of evil qi，resulting in endogenous blood stasis. The author analyzes the internal pathogenesis of the disease from the perspective of weakened function of zang-fu organs and disharmony of qi，blood，yin and yang. Taking “tonifying deficiency and removing blood stasis” as the basic treatment principle，the treatment is based on the three zang-organs of liver，spleen and kidney，and one proven case is attached for evidence. |
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