|
| Progress in the study of pathological mechanisms of heart failure with preserved ejection fraction and intervention with traditional Chinese medicine |
| Hits 392 Download times 140 Received:April 25, 2025 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2025.09.18 |
| Key Words
heart failure with preserved ejection fraction;pathological mechanism;traditional Chinese medicine syndrome differentiation;traditional Chinese medicine;pharmacological mechanism |
| Author Name | Affiliation | E-mail | | LIU Honglin | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LI Yilin | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | OPOKU BONSU FRANCIS | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WU Han | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | JIA Fuyun | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | LENG Ling | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin 301617, China | | | LI Ruiqiao | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin 301617, China | liruiqiao@tjutcm.edu.cn | | WANG Qilong | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin 301617, China
Modern Traditional Chinese Medicine Haihe Laboratory, Tianjin 301617, China | wangqilong_00@tjutcm.edu.cn |
|
| Abstract
|
| Heart failure with preserved ejection fraction（HFpEF） is a heterogeneous clinical syndrome caused by the impaired ability of the heart to cope with the metabolic demands of the body，which leads to microvascular inflammation，metabolic disorders，and oxidative stress. Traditional Chinese medicine（TCM） has unique advantages in the prevention and treatment of heart failure，and TCM diagnosis can enable TCM treatment to achieve precise diagnosis，accurate medication，and clear therapeutic effects. The article reviews the main pathological mechanisms of HFpEF，the three TCM symptomatic subtypes of qi deficiency and blood stasis，qi and yin deficiency and blood stasis，and yang deficiency and blood stasis，as well as the mechanism of the effects of TCM on HFpEF，with a view to providing a new strategy for the clinical management of heart failure with preserved ejection fraction. |
|
|
|
|
|
|
|
