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| The novel treatment strategy for ADPKD based on the theory of kidney deficiency and blood stasis and the therapy of tonifying kidney and promoting blood circulation proposed by national traditional Chinese medicine Master ZHANG Daning |
| Hits 276 Download times 43 Received:October 07, 2025 |
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| DOI
10.11656/j.issn.1672-1519.2026.03.01 |
| Key Words
autosomal dominant polycystic kidney disease;the theory of kidney deficiency and blood stasis;the therapy of tonifying kidney and promoting blood circulation;ZHANG Daning |
| Author Name | Affiliation | E-mail | | DING Sheng | Graduate School of Beijing University of Chinese Medicine, Beijing 100029, China | | | FENG Luda | Xuanwu Hospital, Capital Medical University, Beijing 100053, China | | | CHEN Shu | Graduate School of Beijing University of Chinese Medicine, Beijing 100029, China | | | DONG Shaoning | Tianjin Academy of Tradtional Chinese Medicine Affiliated Hospital, Tianjin 300120, China | | | DENG Yuanyuan | Graduate School of Beijing University of Chinese Medicine, Beijing 100029, China | | | HE Pengfei | Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China | | | WANG Yuqi | Graduate School of Beijing University of Chinese Medicine, Beijing 100029, China | | | ZHANG Mianzhi | Tianjin Academy of Tradtional Chinese Medicine Affiliated Hospital, Tianjin 300120, China
Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China
Tianjin Nankai Hospital, Tianjin 300100, China | zhangmianzhi@vip.sina.com |
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| Abstract
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| Autosomal dominant polycystic kidney disease（ADPKD） is a progressive and incurable hereditary renal disease，which is a common cause of end stage renal disease（ESRD）. “The theory of kidney deficiency and blood stasis” and “the therapy of tonifying kidney and promoting blood circulation” were initiated by national traditional Chinese medicine Master ZHANG Daning，and have now become a common therapy in the treatment of chronic kidney disease with traditional Chinese medicine. Based on “the theory of kidney deficiency and blood stasis” and “the therapy of tonifying kidney and promoting blood circulation”，we summarize the core etiology of ADPKD as “congenital deficiency and acquired injury”. The dynamic development of “deficiency，stasis and toxin” is the key link of the deterioration of the disease. The progression of the disease is as follows：“ADPKD initially affects the spleen and kidney，then involves the liver and kidney in the middle stage，and in the end stage，it often damages multiple viscera. Throughout the entire process，kidney deficiency and blood stasis are consistently present.” Therefore，based on “the theory of kidney deficiency and blood stasis” and “the therapy of tonifying kidney and promoting blood circulation”，the treatment of ADPKD provides a novel reference for clinical diagnosis and therapy. |
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