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Research progress of Zhenqi Fuzheng Preparations in cancer treatment based on the principle of “Fuzheng Quxie”
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DOI   10.11656/j.issn.1672-1519.2026.03.19
Key Words   Fuzheng Quxie;cancer;Zhenqi Fuzheng Preparations;integrative Chinese-Western medicine treatment
Author NameAffiliationE-mail
GUO Luxuan College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		 
ZHANG Ziyuan College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		 
JIANG Tianyue College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		 
DI Ruohan College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		 
ZHENG Xiaoqing College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		 
KONG Xianbin College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		 
MENG Jingyan College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 		mengjy@163.com 
Abstract
    Cancer is a major public health problem that poses a serious threat to public health. Current standard treatments，including surgery，radiotherapy，chemotherapy and targeted therapies，remain limited in terms of efficacy and safety. Existing studies suggest that traditional Chinese medicine，as an adjuvant therapy，can enhance treatment efficacy and reduce therapy-related adverse events when combined with standard care. Zhenqi Fuzheng Granule（ZQFZ），a widely used traditional Chinese medicine formulation among cancer patients，exerts multiple functions including strengthening vital qi，enhancing immune function，modulating the gut microbiota，and alleviating the side effects of chemotherapy. Based on the traditional Chinese medicine principle of “strengthening the body’s resistance and eliminating pathogenic factors”，this paper systematically reviews the traditional Chinese medicine theoretical foundation of ZQFZ in cancer treatment，its active anti-tumor components and pharmacological effects，as well as current clinical research progress，with the aim of providing theoretical support and practical reference for optimizing integrated traditional Chinese medicine and Western medicine strategies in cancer therapy.

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