咳清灵治疗小儿急性支气管炎痰热壅肺证的临床研究

Clinical Study on Keqingling in Treating Lung Phlegm Heat Syndrome in Children with Acute Bronchitis

关键词:  咳清灵  小儿急性支气管炎  痰热壅肺证

Key words:  Keqingling  acute bronchitis in children  lung phlegm heat syndrome

摘要:

[目的]验证咳清灵治疗小儿急性支气管炎痰热壅肺证的有效性与安全性。[方法]采用随机分组、双盲双模拟、平行对照的方法进行临床对照研究。[结果]试验组的愈显率为85 %,中医证候愈显率为90 %,均明显高于对照组 (P<0.01)。试验组对咳嗽、咯痰、症状积分,以及脉纹的改善作用,均明显优于对照组 (P<0.05或P<0.01)。两组患儿血白细胞计数和X线胸片异常均有明显改善 (P<0.05或P<0.01)。安全性指标观测未发现异常改变。[结论]咳清灵对小儿急性支气管炎痰热壅肺证有较好的治疗作用,且临床应用比较安全。

Abstract:

[Objective] To verify the effectiveness and reliability of Keqingling in treating lung phlegm heat syndrome in children with acute bronchitis. [Methods] Eighty patients were randomly divided into two groups,compared with corre-sponding control. [Results] The effective rate was 85% in the treated group,which was higher significantly than that in the control group P<0.01).The improvement of some symptoms,including cough,abnormal pulses,finger mark and the difference of score between pre-treatment and post-treatment,in the treated group was significantly higher than those in the control group(P<0.05-0.01).The WBC count and X-ray film were remarkably improved after treatment in both groups(P<0.05-0.01).No abnormal changes of reliability markers had been observed. [Conclusion] Keqingling possesses better effects and clinical reliability in treating lung phlegm heat syndrome in children with acute bronchitis.