毓宫胶囊对肾阳虚子宫发育不良大鼠子宫血液灌注量的影响

Influence of Yugong Capsule on Uterus Blood Perfusion in Rats with Uterus Hypogenesis Caused by Kidney-yang Deficiency

关键词:  毓宫胶囊  肾阳虚  子宫发育不良  子宫灌注不良  实验研究

Key words:  Yugong capsule  Deficiency of Kidney-yang  uterus hypogenesis  uterus perfusion deficiency  experiment research

摘要:

[目的]观察毓宫胶囊对子宫发育不良大鼠子宫动脉血管数及灌注量的影响。[方法]将健康雌性SD大鼠分为4组,正常组、模型组、右归丸组、毓宫胶囊组。分别饲喂不同药剂,连续18d后处死,测量各组大鼠子宫肌层血管数及对肌层动脉半径的影响。[结果]毓宫胶囊组较模型组大鼠在增加子宫肌层血管数上具有显著性差异(P<0.05),且使大鼠子宫肌层血管半径明显增加,与模型组大鼠比较有极显著性差异(P<0.01)。[结论]毓宫胶囊能改善子宫的血液灌注量,使肾阳虚型子宫发育不良大鼠子宫肌层厚度增加,促进子宫生长发育。

Abstract:

[Objective] the effect of Yugong(uterus-nourishing)capsule on the number of uterus arterioles and blood perfusion in uterus hypogenesis rats. [Methods] The female healthy SD rats were divided randomly into four groups:normal group,model group,Yougui pill group and Yugong capsule group.They were fed with different medicament respec-tively and killed eighteen days later.The vascular number of myometrium and their diameter of rats in each group were measured to observe the effect of different management. [Results] Yugong capsule could markedly increase not only the number but also the diameter and had obvious statistical difference compared with model group(P<0.01). [Conclusion] Yugong capsule may improve the uterus blood perfusion and increase the depth of myometrium in rats with uterus hypo-genesis caused by Kidney-yang deficiency.So Yugong capsule may facilitate uterus growth and development.