| 摘要: |
| [目的]采用新的中药抑菌实验方法对五倍子水煎剂进行了100株溶血葡萄球菌等凝固酶阴性葡萄球菌(CNS)体外抗菌活性检测。[方法]将五倍子水煎剂采用醇脂稀释法,用M-H琼脂对五倍子等进行定量抗菌实验。[结果]五倍子水煎剂对溶血葡萄球菌(staphylococcusheamolyticus)等凝固酶阴性葡萄球菌的抗菌活性均较好,其MIC50均为0 051mg/mL(1:10240),对溶血葡萄球菌和里昂葡萄球菌(S.lugdunensis)的MIC90 均为0.203mg/mL(1:2560),对44株人葡萄球菌(S.hominis)等的MIC90 为0.203mg/mL(1:2560)。[结论]此项研究为临床治疗由凝固酶阴性葡萄球菌引起的感染,提供了实验依据。 |
| 关键词: 五倍子 凝固酶阴性葡萄球菌 溶血葡萄球菌 里昂葡萄球菌 人葡萄球菌 抗菌活性 |
| DOI：10.11656/j.issn.1672-1519.2004.05.28 |
| 分类号: |
| 基金项目:河北省科学技术厅计划内课题(编号:01276-2111D) |
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| Antibacterial Activity of Galla Chinensis against100Strains of CNS Including Hemolytic Staphylococci in vitro |
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LI Zhong-xing, WANG Xiu-hua, MENG Xiao-jie
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The Second Hospital of Hebei Medical University, ShiJia zhuang 050000, China
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| Abstract: |
| [Objective] To determine the antibacterial activity of decoction of Galla Chinensis against100strains of coagu-lase-negative Staphylococci(CNS)in vitro by a new method of antibacterial test for traditional Chinese medicine. [Methods] The decoction of Galla Chinensis was diluted with agar and an antibacterial experiment was carried by M-H a-gar. [Result] The antibacterial effect of galla Chinensis against CNS(hemolytic Staphylococci etc)was marked(MIC50:0.051mg/mL,1:10240),and the MIC90against S.heamolyticus and S.lugdunensis was 0.203mg/mL(1:2560).The MIC90 against 44 strains S.hominis etc was0.203mg/mL(1:2560). [Conclusion] The study provided experimental basis for the cure of infection caused by CNS. |
| Key words: Galla Chinensis coagulase-negative Staphylococci S.heamolyticus S.lugdunensis S.hominis antibacterial activity |
