灯盏细辛注射液对2型糖尿病并发末梢神经炎血液流变学与血脂改变的影响

Therapeutic Effect of Shortscape Fleabane Injection in Treating Diabetes 2 Complicated with Peripheral Neuritis,Abnormal Rheology and Hyperlipemia

关键词:  糖尿病末梢神经炎  血液流变学  血脂  灯盏细辛注射液

Key words:  non-insulin dependent diabetes complicated with peripheral neuritis  haemorheology  blood lipid  SF injection

摘要:

[目的]观察分析灯盏细辛注射液治疗2型糖尿病并发末梢神经炎的血液流变学及血脂变化。[方法]治疗组应用灯盏细辛注射液滴注,对照组应用氢溴酸山莨菪硷注射滴注,观察临床症状、血液流变学、血脂、神经传导速度等变化。[结果]治疗组治疗后全血黏度、血球压积、纤维蛋白元明显低于治疗前,有显著性差异,P<0.01;治疗组治疗后甘油三酯(TG)、胆固醇(TC)、低密度脂蛋白(LDL-c)均有降低,有显著性差异P<0.05,高密度脂蛋白(HDL-c)有所增高,但增高不明显P>0.05;治疗组总有效率88.64%,优于对照组,有显著性差异P<0.01;治疗组腓神经运动和感觉传导速度改善明显P<0.05。[结论]灯盏细辛注射液显著改善2型糖尿病并发末梢神经炎患者的血液流变性及脂代谢,治疗2糖尿病并末梢神经炎临床疗效肯定。

Abstract:

[Objective] To observe and analyze the effect on Shortscape Fleabane(SF) injection on haemorheology and hyperlipemia in non-insulin dependent diabetes complicated with peripheral neuritis.[Methods] The therapy group was administered SF injection.The control group was administered Anisodamine injection.The change of clinical symptoms,haemorheology,blood lipid,conductive velocity of nerve,etc.was determined.[Result] The total effective rate of therapy group was 88.64% and superior to that of control group(P<0.01).The whole blood viscosity,hematocrit,fibrinogen,TC,TG,LDL-c were decreased markedly in therapy group after treatment(P<0.05).But the HDL-c increased in some extents and there was no significant difference(P>0.05).The therapy group was improved obviously in peroneal nerve motion and the conductive velocity of sensory nerve(P<0.05).[Conclusion] The SF injection may improve the haemorheology and lipid metabolism of patients from non-insulin dependent diabetes complicated with peripheral neuritis.The SF injection has definitely therapeutic effect in treating non-insulin dependent diabetes complicated with peripheral neuritis.