甲宁方治疗肝阳上亢、血瘀痰凝型甲状腺功能亢进症31例临床观察

Clinical effect of Jianing Prescription in treating hyperthyroidism in 31 patients with hyperactivity of liver-yang and blood stasis and phlegm coagulation

关键词:  甲宁方  肝阳上亢、血瘀痰凝证  甲状腺功能亢进症  临床观察

Key words:  Jianing prescription  hyperactivity of liver-yang and blood stasis and phlegm coagulation  hyperthyroidism  clinical observation

摘要:

[目的] 观察甲宁方对肝阳上亢、血瘀痰凝证甲状腺功能亢进症的治疗效果。[方法] 将临床诊断为甲状腺功能亢进症,中医证属肝阳上亢、血瘀痰凝证的患者31例纳入治疗组,给予甲宁方治疗,8周为1个疗程,进行治疗前后对照比较。[结果] 甲宁方能有效改善患者三碘甲状腺原氨酸(T3)、甲状腺激素(T4)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺素(TSH)等指标,治疗前后比较有显著性差异(P<0.05)。并且有促进甲状腺刺激抗体(TSAb)转阴的作用。[结论] 临床观察表明甲宁方治疗肝阳上亢、血瘀痰凝证甲状腺功能亢进症疗效满意并具有改善甲状腺功能,调节免疫的作用,且无明显不良反应。

Abstract:

[Objective] To observe the therapeutic effect of Jianing(calming thyroid) Prescription in treating hyperthyroidism with hyperactivity of liver-yang and blood stasis and phlegm coagulation.[Methods] Thirty-one patients consisting with above diagnosis were enrolled into the treatment group treated with Jianing Prescription.After a treatment course of eight weeks the therapeutic effect was compared before and after therapy.[Results] Jianing Prescription could effectively improve the parameters T3,T4,FT3,FT4,TSH and so on in patients with significant difference before and after treatment(P<0.05).The prescription had also effect of transforming the positive TSAb to negative.[Conclusions] Jianign Prescription has satisfactory effect in treating hyperthyroidism with hyperactivity of liver-yang and blood stasis and phlegm coagulation.It can improve the thyroid function,regulate the immunology without adverse effect.