活血软坚法治疗慢性肾小球肾炎的临床观察

Treatment of chronic glomeruli nephritis with Huoxue Ruanjian Method

关键词:  活血软坚法  慢性肾小球肾炎  临床观察

Key words:  Huoxue Ruanjian Method  treatment  chronic glomeruli nephritis

摘要:

[目的]观察活血软坚法治疗慢性肾小球肾炎的临床疗效。[方法]选择60例慢性肾炎患者,随机分为治疗组和对照组,疗程均为12周,检测患者治疗前后血尿素氮(BUN)和肌酐(Cr),24h尿蛋白定量等指标,并进行统计学分析。[结果]两组治疗后24h尿蛋白与治疗前相比较,均明显下降,两组间治疗后相比较,治疗组下降明显,与对照组相比具有显著性差异。两组内患者血Cr治疗后与治疗前比较,均明显下降,具有显著性差异,两组间治疗后血Cr相比,无显著性差异。两组内患者血BUN治疗后与治疗前比较,均明显下降,具有显著性差异,两组间治疗后相比较,治疗组与对照组比有显著性差异。[结论]活血软坚法治疗慢性肾炎,较单纯应用赖诺普利能够更好减轻蛋白尿,降低血Cr,值得临床广泛应用。

Abstract:

[Objective] To observe the clinical effect of Huoxue(promoting blood circulation) Ruanjian(softening the hard mass) Method in treating chronic glomeruli nephritis. [Methods] Sixty patients with chronic nephritis were randomly divided into treatment group and control group. The change of BUN, Cr and 24 h urine protein quantitative determination 12 weeks after treatment was determined and the statistic analysis was carried out. [Results] There were obvious differences before and after treatment in the content of BUN, Cr and 24 h urine protein. Compared to control group, there were also obvious differentiations in the content of BUN, Cr and 24h urine protein. [Conclusions] Huoxue Ruanjian Method may treat chronic nephritis, having preferable effect in decreasing urine protein and blood Cr. It is worth general clinical application.