退黄降氨汤灌肠治疗肝性脑病76例

Treatment of hepatic encephalopathy by enema with tuihuang and jiangan decoction in 76 patients

关键词:  肝性脑病  退黄降氨汤  乳果糖  保留灌肠

Key words:  hepatic encephalopathy  tuihuang and decreasing ammonia decoction  lactulose  retention enema

摘要:

[目的]观察退黄降氨汤保留灌肠治疗肝性脑病的疗效。[方法]将152例肝性脑病患者随机分为治疗组76例,对照组76例,均采用综合治疗;治疗组加用退黄降氨汤治疗,对照组加用乳果糖治疗,2组疗程均为7d。两组患者治疗前后做血氨检查,观察患者清醒时间。[结果]治疗组降低血氨优于对照组(P<0.05),且缩短昏迷的时间。在疗效方面,治疗组有效率为82.9%(63/76);对照组有效率为67.1%(51/76),两组比较有显著性差异(P<0.01)。[结论]退黄降氨汤保留灌肠可有效地降低血氨,促进患者苏醒,缩短昏迷的时间。

Abstract:

[Objective] To observe the clinical effect of enema with tuihuang(eliminating jaundice) and jiangan( decreasing the ammonia retention) decoction in treating hepatic encephalopathy. [Methods] One hundred and fifty-two patients with hepatic encephalopathy were randomly divided into treatment group (76 cases) and control group (76 cases). Tuihuangjiangan decoction was added in treatment group and lactulose treatment added to the control group. The treatment course was 7 days. The blood ammonia was determined before and after treatment. The resuscitation time was recorded. [Results] The effect of decreasing ammonia was better in treatment group than that of the control group (P<0.05) and the time in a coma was shorten. The effective rate in the treatment group was 82.9% (63/76); and 67.1% (51/76) in control group with significant difference(P<0.01). [Conclusion] Enema with Tuihuang and decreasing ammonia retention was effective in lowering blood ammonia. It can promote the patients for regained consciousness and can shorten the time in coma.