| 摘要: |
| [目的]优选苦参的半仿生提取法工艺条件。[方法]采用UL(91×33)均匀实验设计,以苦参碱、氧化苦参碱、苦参总碱、高效液相色谱(HPLC)总面积、干浸膏为指标综合评判,优选苦参半仿生提取的工艺条件。[结果]3煎用水的pH值依次为2.2008、7.4685、8.9890;3煎总计时间为3.9180h。[结论]结合生产实际,确定3煎用水的pH值依次为2.0、7.5、9.0;提取时间依次为2.0、1.0、1.0h。 |
| 关键词: 苦参 半仿生提取法 均匀设计 多成分指标 综合评判 |
| DOI：10.11656/j.issn.1672-1519.2010.01.31 |
| 分类号: |
| 基金项目:国家自然科学基金课题(30701110) |
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| Even-designed and optimized technology for semi-bionic extraction of Sophora Flavescens |
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WANG Ying-zi1, HUI Jian-Guo2, ZHANG Zhao-wang2
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1.Beijing University of TCM, Beijing 100102, China;2.Shandong University of TCM, Jinan 250014, China
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| Abstract: |
| [Objective] To optimize the technique of semi-bionic extraction (SBE) for Sophora Flavescens.[Methods] Based on the UL (91×33)even-design,matrine,oxymatrine,total alkaloids,total area of HPLC and dry extract were used as indexes to optimize the technology of SBE for Sophora Flavescens.[Results] The pH value of 3 times of extraction is 2.2008,7.4685 and 8.9890,respectively.The total extracting time is 3.9180 hours.[Conclusion] Based on the manufacture practice,the pH value of extraction of 3 times is 2.0,7.5 and 9.0,respectively and the extracting time is 2 hours,1 hour and 1 hour in turn. |
| Key words: Sophora Flavescens semi-bionic extraction even-design multi-component indexes comprehensive evaluation |
