| 摘要: |
| [目的]研究芍药苷在不同温度及pH条件下的稳定性。[方法]采用高效液相色谱法在不同温度及pH条件下,测定芍药苷在不同时间的含量变化。[结果]芍药苷在pH=9.0条件下,高于60℃在3h完全降解,在酸性条件下不降解。[结论]芍药苷在酸性条件下稳定,在碱性条件下随温度的升高,降解加速。 |
| 关键词: 芍药苷 温度 pH 稳定性 |
| DOI：10.11656/j.issn.1672-1519.2010.04.37 |
| 分类号: |
| 基金项目:国际科技合作计划项目(2007DFC31670);国家科技支撑计划项目(2007BAI47B01);国家科技重大专项(2009ZX09311-002) |
|
| Study on stability of paeoniflorin |
|
XIE Jiang-chun, LIU Zhi-dong, TIAN Hui
|
|
Tianjin University of TCM, Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin 300193, China
|
| Abstract: |
| [Objective] To investigate the stability of paeoniflorin in different pH and temperature. [Methods] The changes of paeoniflorin after placed for some time were determined by HPLC in different temperature and pH values. [Results] Paeoniflorin was completely degradated after placing at pH 9.0 or above a temperature of 60℃ for 3 h.No degradation was found in acid conditions. [Conclusion] paeoniflorin was stable in acid medium and degradation was accelerated when temperature increased or in a basic condition. |
| Key words: paeoniflorin temperature pH stability |
