缺血性中风气虚证出现频率与神经功能缺损程度的关系初探

Study on the correlation between frequency of Qi deficiency and neurological deficit in patients with ischemic stroke

关键词:  缺血性中风  气虚证  频率  神经功能缺损

Key words:  ischemic stroke  Qi deficiency  frequency  neurological deficiency

摘要:

[目的]通过比较气虚证出现频率不同分组间神经功能缺损评分的差异,探讨缺血性中风气虚证出现频率与神经功能缺损程度的关系。[方法]选取缺血性中风发病72h内患者605例,动态采集患者发病1-14 d及发病28、90 d时《缺血性中风证候要素诊断量表》、美国国立卫生研究院卒中量表(NIHSS)评分,根据气虚证出现的时点频率将患者分为气虚证出现时点≤8个组(298例),气虚证出现时点>8个组(307例)。比较气虚证出现频率不同分组间神经功能缺损评分的差异。[结果]各时点两组神经功能缺损程度评分差异均有统计学意义(P<0.01);两组组内各时点神经功能缺损程度评分比较,差异均有统计学意义(P=0.000),随时间的延后,两组神经功能缺损程度评分均逐渐降低。两组发病14 d与入组当天神经功能缺损程度评分差值比较,差异有统计学意义(P<0.05),气虚证出现时点≤8个组发病14 d与入组当天神经功能缺损程度评分差值大。[结论]缺血性中风气虚证出现时点多的患者神经功能缺损程度较气虚证出现时点少的患者更重,且气虚证出现时点多的患者发病14 d时神经功能缺损程度的改善无气虚证出现时点少的患者明显,积极扶助正气治疗对改善中风病的神经功能缺损程度具有重要作用。

Abstract:

[Objective] To study the correlation between frequency of Qi deficiency and neurological deficit in patients with ischemic stroke by comparing the neurological deficit scores between groups with difference in frequency of Qi deficiency.[Methods] The 605 patients with stroke attacked within 72 h were enrolled in this study.Dynamically collecting the scores of ischemic stroke syndrome factors diagnostic scale and NIHSS(The National Institutes of Health Stroke Scale) of the first to 14th day and 28th,90th day after onset,Qi deficiency appearing point ≤ 8(298) and appearing point 8(307) were grouped according to the frequency of Qi deficiency.The difference of neurological deficit scores among the groups were compared.[Results] The neurological deficit scores at each time point between two groups were significantly different(P<0.01);The differences of neurological deficit scores at each time point within each group were statistically significant(P=0.000);as the time delayed the scores were decreased gradually in both groups.Comparing the neurological deficit score between 14th day and the first day,the difference of two groups was statistically significant(P<0.05).The difference of neurological deficit score was also found in group of appearing point ≤ 8(298) between 14th day after onset and the first day.[Conclusion] Neurological deficit score of ischemic stroke in patients with more appearing time was severer than patients with less time point.The improvement of neurological deficit score of 14th day in patients with more appearing time point were more significant than those with less point.Actively invigorating healthy Qi plays an important role in improving neurological deficit scores of stroke patients.