益气养阴活血中药治疗慢性心力衰竭急性加重36例临床疗效观察

Clinical curative effect on chronic heart failure 36 patients in acute exacerbation treated with benifiting Qi for nurishing Yin and activating blood of traditional Chinese medicine

关键词:  参麦注射液  注射用红花黄色素  慢性心力衰竭急性加重期  气阴两虚证

Key words:  Shenmai injection  Safflower yellow injection  acute exacarbetion of chronic heart failure  deficiency of Qi and Yin syndrome

摘要:

[目的] 评价参麦注射液合注射用红花黄色素治疗慢性心力衰竭急性加重期气阴两虚证的临床疗效及安全性。[方法] 将72例慢性心力衰竭急性加重期气阴两虚证患者随机分为治疗组和对照组，两组均给予西药规范治疗，治疗组在西药规范治疗的基础上联合参麦注射液合注射用红花黄色素静脉滴注，疗程10 d.[结果] 治疗组在中医证候方面显着改善，且明显优于对照组（P<0.05或P<0.01）;心功能改善情况与对照组比较差异有统计学意义（P<0.05）;脑钠肽（BNP）显着降低，与对照组比较差异有统计学意义（P<0.05）.[结论]在西药规范治疗基础上，联合参麦注射液合注射用红花黄色素治疗慢性心力衰竭急性加重期临床疗效确切，且具有较好的安全性。

Abstract:

[Objective] To evaluate the clinical effect and toxicity of Shenmai injection and Safflower yellow injection for acute exacarbetion of chronic heart failure. [Methods] The 72 patients in acute exacarbetion of chronic heart failure with deficiency of Qi and Yin syndrome were divided two groups randomly. Control group were treated by routine western medicine. Treat group were added with Shenmai injection and Safflower yellow injection with the underlaying of Western medicine for 10 days. [Results] The effective rate of the improvement of traditional Chinese medicine symptoms, the improvement of heart function, and the brain natriuretic peptide in treat group were better than that in control group, significantly(P<0.05 or P<0.05). [Conclusion] Shenmai injection and Safflower yellow injection are effective for treatment for acute exacarbetion of chronic heart failure.