支气管哮喘患者穴位贴敷治疗中皮肤反应与临床疗效的相关性研究

Correlation research between skin reactions and clinical efficacy of application method on acupoint in treatment of asthma

关键词:  哮喘  穴位贴敷  皮肤反应  临床疗效

Key words:  asthma  acupoint sticking  skin reaction  clinical efficacy

摘要:

[目的] 观察穴位贴敷法治疗支气管哮喘的临床疗效，探讨穴位贴敷治疗中皮肤反应程度与临床疗效的相关性。[方法] 根据323例哮喘患者贴敷后的皮肤反应程度分为无反应组、轻度反应组、中度反应组和重度反应组，分析各组在不同时间点主要症状积分，次要症状积分，哮喘控制测试（ACT）评分，第一秒用力呼气容积（FEV1）及冬季发病次数的变化规律。[结果] 各组主要症状积分，次要症状积分、ACT评分治疗前与治疗后各时间点，治疗后与6个月后相比均有统计学意义（P<0.05）。FEV1治疗前与治疗6个月后相比有统计学意义（P=0.001）。各组治疗前与治疗后冬季发作次数的差值具有统计学意义（P<0.05）。主要症状积分、ACT评分在治疗后各时间点中，无反应组与轻、中、重各组相比均有统计学意义（P<0.05）。次要症状积分、FEV1在6个月后，无反应组分别与轻、中、重各组比较，有统计学意义（P<0.01）。主要症状积分、ACT评分、次要症状评分、FEV1在治疗6个月后，轻、中度反应组与重度反应组之间有统计学意义（P<0.05）。[结论] 穴位贴敷疗法治疗哮喘临床疗效确切，同时具有近期疗效及远期疗效。贴敷治疗中皮肤反应程度与临床疗效具有相关性，有皮肤反应各组在近期疗效、远期疗效上均优于无反应组，轻、中、重各反应组在近期疗效上无统计学意义，但远期疗效上轻、中度皮肤反应优于重度皮肤反应。

Abstract:

[Objective] To observe the clinical efficacy of acupoint application method in treatment of bronchial asthma and investigate the relationship between skin reactions and clinical efficacy.[Methods] According to the degree of skin reactions, 323 clinical cases of herbal plaster were divided into non-reaction skin group,mild reaction skin group, moderate reaction skin group and severe skin reaction group, analyzing the changing rule of the different group of main symptom scores, minor symptom scores, ACT scores, FEV1 and attack times in winter.[Results] Comparing with the pre treatment of main symptom scores, minor symptom scores, ACT scores with each point of time of post treatment, showed the significant statistics difference (P<0.05), post treatment and 6 months after equally had statistics difference, FEV1 had significant difference between the pre treatment and 6 months after (P=0.001). The attack times in the winter between the pre treatment and post treatment had statistical difference(P<0.05). Comparing non-reaction skin group with mild, moderate, severe skin reaction group, main symptom scores and ACT scores had statistical difference each point of time of post treatment (P<0.05). Minor symptom scores and FEV1 equally had statistical difference in 6 months after(P<0.05). Comparing mild and moderate skin reaction group with severe skin reaction group, main symptom scores, minor symptom scores. ACT scores and FEV1 had statistical difference in 6 months after (P<0.05), but mild and moderate skin reaction group had no statistical significance(P>0.05).[Conclusion] Drug acupoint application of bronchial asthma having the recent and long-term clinical efficacy, skin reaction have the relation with the clinical efficacy. Abnormal reaction skin group have more significant clinical efficacy in recent and long-term, mild, moderate, severe skin reaction group have no significant difference, mild and moderate skin reaction better than the severe skin reaction.