| 摘要: |
| [目的] 采用随机对照方法，观察三黄益肾胶囊治疗早期糖尿病的临床疗效。[方法] 将110例早期糖尿病肾病患者随机分为3组，其中三黄益肾组36例，给予三黄益肾胶囊治疗；三黄益肾联合胰激肽原酶组38例，给予三黄益肾胶囊与胰激肽原酶肠溶片治疗；胰激肽原酶组36例，给予胰激肽原酶肠溶片治疗。3个月为1个疗程，疗程结束后，比较3组治疗前后有关指标。[结果] 治疗后3组的空腹血糖、餐后2 h血糖、胆固醇、甘油三酯、血压、24 h尿微量白蛋白均明显降低，具有统计学差异（P<0.01）。其中三黄益肾联合胰激肽原酶组24 h尿微量白蛋白较其他2组降低更为明显，具有统计学差异（P<0.05）。[结论] 三黄益肾胶囊联合胰激肽原酶肠溶片可有效治疗早期糖尿病肾病。 |
| 关键词: 糖尿病肾病 早期 三黄益肾胶囊 胰激肽原酶肠溶片 |
| DOI：10.11656/j.issn.1672-1519.2017.02.08 |
| 分类号: |
| 基金项目:河北省中医药管理局课题（2015301）。 |
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| A randomized controlled study of early diabetic nephropathy of Sanhuang Yishen capsules treatment |
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LV Shu-quan1, LI Shu-lin2, ZHANG Shu-fang1, SU Xiu-hai1, YU Wen-xia1, GUO Rui-qing1
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1.Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine of Hebei Province, Cangzhou 061001, China;2.Cangzhou Hospital of Traditional Chinese Medicine, Cangzhou 061001, China
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| Abstract: |
| [Objective] To observe the clinical effect of Sanhuang YiShen capsules in the treatment of early diabetes using randomized controlled method.[Methods] The 110 cases of patients with early diabetic nephropathy were randomly divided into 3 groups, Sanhuang Yishen Capsules group with 36 cases, Sanhuang Yishen combined with pancreatic kininogenase group with 38 cases and pancreatic kininogenase group with 36 patients. 3 months for 1 course, after the end of treatment, related indexes were compared with among 3 groups.[Results] Fasting blood glucose, postprandial 2 h blood glucose, cholesterol, triglyceride, blood pressure and 24 h urine micro albumin were significantly lower after treatment in 3 groups(P<0.01), and the 24 h urine micro albumin was significantly lower than the other 2 groups. The difference was statistically significant (P<0.05).[Conclusion] Sanhuang Yishen capsules combined with pancreatic kininogenase are effective in the treatment of early diabetic nephropathy. |
| Key words: diabetic nephropathy early stage Sanhuang Yishen capsule pancreatic kininogenase enteric-coated tablet |
