整体针药法治疗发作期支气管哮喘临床观察

Clinical observation on the treatment of bronchial asthma in the stage of the attack by the holistic acupuncture and medicine therapy

关键词:  支气管哮喘  整体针药法  射干麻黄汤  嗜酸性粒细胞阳离子蛋白

Key words:  bronchial asthma  holistic acupuncture and medicine therapy  Shegan Mahuang decoction  eosinophil cationic protein

摘要:

[目的] 观察整体针药法治疗发作期支气管哮喘（BA）的临床疗效。[方法] 将60例辨证为寒哮证发作期的BA患者随机分为对照组30例，常规西药治疗；治疗组30例，在常规西药的基础上加用内服射干麻黄汤加减，外用穴位针刺及穴位敷贴治疗。两组均治疗1周。观察治疗后患者的临床疗效、肺功能及白介素（IL）-5、IL-10、嗜酸性粒细胞阳离子蛋白（ECP）的变化。[结果] 治疗后，对照组总有效率为73.33%，治疗组总有效率为93.33%，两组比较差异有统计学意义（P<0.05）；治疗组对肺功能的改善优于对照组（P<0.05）；治疗后，治疗组患者IL-5、嗜酸性粒细胞（EOS）及ECP水平低于对照组（P<0.05），IL-10水平高于对照组（P<0.05）。[结论] 整体针药法联合常规西药治疗BA优于单用常规西药治疗。

Abstract:

[Objective] To observe the clincal effect of the holistic acupuncture and medicine therapy on treating the bronchial asthma(BA) in the stage of the attack.[Methods] The 60 cases of syndrome differentiation for cold asthma attack period of BA patients were randomly divided as control group (30 cases) conventional Western medicine treatment, treatment group (30 cases) treated with oral administration of Shegan Mahuang decoction modified on the basis of routine treatment of Western medicine, topical acupuncture and acupoint post treatment. Two groups were treated for one week. The clinical curative effect, pulmonary function and the changes of IL-5, IL-10 and ECP in the patients after treatment were observed.[Results] After treatment, total effective rate of the control group was 73.33%, and treatment group the total efficiency was 93.33%. The difference between two groups had statistical significance (P<0.05). Treatment group on lung function was better than the control group (P<0.05). After treatment, treatment group, IL-5 and eosinophils and ECP levels lower than that in the control group (P<0.05), IL-10 levels higher than control group (P<0.05).[Conclusion] Clinical efficacy of holistic acupuncture and medicine method combined with conventional Western medicine treatment of BA is better than single conventional Western medicine treatment.