乌灵胶囊对肺结核患者并发焦虑症状的疗效观察

Curative effect evaluation of Wuling capsule on pulmonary tuberculosis complicated with anxiety

关键词:  乌灵胶囊  肺结核  焦虑症

Key words:  Wuling capsule  pulmonary tuberculosis  anxiety

摘要:

[目的] 探讨乌灵胶囊对肺结核患者并发焦虑症状的临床治疗效果及安全性。[方法] 将86例肺结核并发焦虑症状的患者采用随机数字法分为观察组与对照组，每组各43例，两组患者均给予2HRZE/4HR抗结核治疗及心理干预，观察组在此基础上同时加服乌灵胶囊。观察两组患者的肺结核吸收情况及临床疗效，并采用汉密尔顿焦虑量表（HAMA）对治疗前及治疗8周后两组患者焦虑症状进行评分，比较两组患者HAMA评分情况；并观察药物不良反应。[结果] 治疗后对比两组患者肺结核治疗总有效率，观察组为81.4%，对照组65.1%；两组疗效比较差异无统计学意义（P>0.05）。治疗8周后两组患者HAMA评分均较治疗前降低，治疗后观察组评分明显低于对照组，差异有显著统计学意义。两组均无明显不良反应。[结论] 在正规抗结核治疗的基础上，乌灵胶囊能有效改善肺结核患者并发的焦虑症状，且不良反应少，临床可推广使用。

Abstract:

[Objective] To observe efficacy and safety of Wuling capsules in the treatment of pulmonary tuberculosis complicated with anxiety.[Methods] The 86 patients with pulmonary tuberculosis with anxiety were randomly divided into the observation group and control group, 43 patients for each group. Two groups of patients were given 2HRZE/4HR anti-tuberculosis treatment and psychological intervention. At the same time, patients in the observation group were given Wuling capsules. The TB absorption situation and clinical effect of two groups were observed. The HAMA score before treatment and after treatment for 8 weeks was evaluated. Adverse reactions were observed.[Results] The total effective rate of two groups was compared after treatment, the observation group was 81.4%, 65.1% in control group. There was no statistically significant difference between the two groups (P>0.05). HAMA score has significant difference between two groups after treatment. Two groups had no obvious adverse reactions.[Conclusion] Wuling capsules combined with anti-tuberculosis drugs has remarkable effect on pulmonary tuberculosis complicated with anxiety with high clinical applicable value, and shows less adverse reactions, can be recommended in clinical.