慢性疲劳基本中医证型与心率变异及病程相关性分析

Analysis of correlation between basic traditional Chinese medicine syndrome types of chronic fatigue and heart rate variability and its course

关键词:  慢性疲劳  心率变异  中医证型  病程

Key words:  chronic fatigue  heart rate variability  traditional Chinese medicine syndrome type  course of disease

摘要:

[目的] 观察肝郁化火型及肾气亏虚型慢性疲劳患者的心率变异（HRV）特点及病程长短，分析慢性疲劳不同中医证型与HRV及病程的关系。[方法] 选择肝郁化火型及肾气亏虚型慢性疲劳患者各50例，并设健康对照组50例，均进行HRV分析检测，观察其时域、频域指标，并比较病程长短。[结果] 两组患者HRV均有下降，肾气亏虚组>肝郁化火组，肝郁化火组LF/HF>2，肾气亏虚组LF/HF正常，肝郁化火组病程明显短于肾气亏虚组。[结论] 两组患者均存在自主神经功能异常，肝郁化火组以交感神经亢奋为主，肾气亏虚组以HRV下降为主，病程可能提示疾病由实转虚及HRV变化的过程。

Abstract:

[Objective] To observe the characteristics of heart rate variability (HRV) and duration of chronic fatigue in patients with kidney qi deficiency type and pathogenic fire derived from stagnation of liver qi type, and to analyze the relationship between HRV, course of chronic fatigue and different traditional Chinese medicine (TCM) syndrome types.[Methods] Fifty patients with kidney qi deficiency, fifty with pathogenic fire derived from stagnation of liver qi, and fifty healthy subjects as control group were selected respectively. The HRV analysis was performed in these subjects to observe the time threshold and frequency threshold, as well as the length of its course was compared.[Results] The HRV of the two groups decreased, and the kidney qi deficiency group was higher than the group with pathogenic fire derived from stagnation of live qi. The LF/HF of kidney qi deficiency was normal and that of the latter group>2, while the disease duration of the former was longer than the latter.[Conclusion] There was abnormal autonomic neurological dysfunction in both groups. The sympathetic hyperactivity was mainly in the latter group, and the reduction of HRV was mainly in the kidney qi deficiency group. The duration of disease may indicate the change of deficiency transformed from excess and HRV of the disease.