肾康注射液联合血液透析对终末期肾病患者营养状况的影响

Effect of Shenkang injection combined with hemodialysis treatment on nutriture levels in patients with end stage renal disease

关键词:  慢性肾功能衰竭  肾康注射液  血液透析  营养状况

Key words:  chronic renal failure  Shenkang injection  hemodialysis  nutritional status

摘要:

[目的]探讨肾康注射液联合血液透析对终末期肾病患者营养状况的影响。[方法]选择南京市第一医院血液净化中心收治的120例终末期肾病患者，将所有患者随机分为2组，治疗组予以肾康注射液联合血液透析治疗措施，对照组予以血液透析措施，每组各60例。测定治疗前后两组患者的肾功能、营养状况、电解质、中医证候疗效的改善情况，以及评定疗效，同时对药物不良反应进行记录与比较。[结果]治疗后，治疗组中医证候疗效改善明显，红细胞计数（RBC）、血红蛋白（HGB）、血清总蛋白（TP）、血清白蛋白（ALB）水平及有效率（83.33%）与对照组比较差异具有统计学意义（P<0.05）。与治疗前比较，治疗后两组患者的肾功能及营养状况相关指标、电解质相关指标、中医证候疗效均改变明显（P<0.05）。治疗期间，所有患者均未出现不良反应。[结论]肾康注射液联合血液透析可较好改善终末期肾病患者的症状及营养状况，提高疗效，且安全性较好。

Abstract:

[Objective] To study the effect of Shenkang injection combined with hemodialysis treatment on nutriture levels in patients with (end stage renal disease).[Methods] A total of 120 patients with (end stage renal disease) who received hemodialysis treatment in our hospital were selected and randomly divided into two groups, the observation group received Shenkang injection treatment in the process of dialysis, and the control group only received hemodialysis. The 8 weeks after treatment, serum was collected to determine the levels of renal function indexes,nutritional status indexes, electrolyte and traditional Chinese medicine(TCM) syndrome, evaluate the curative effect and record the adverse drug reactions.[Results] After treatment, the level of RBC, HGB, TP, ALB and the total efficiency of TCM syndrome in the control group was 83.33%. The treatment group was better than the control group (P<0.05). Compared with before treatment, the renal function and nutritional status, electrolyte related indicators and TCM syndromes of the two groups were significantly changed after treatment (P<0.05). There were no abnormalities in the routine tests.[Conolusion] Shenkang injection combined with hemodialysis treatment helps to improve electrolyte, has good safety in patients with end stage renal disease.