针灸改善脓毒症患者胃肠功能障碍的临床观察

Clinical observation of acupuncture on improving septic gastrointestinal dysfunction patient

关键词:  针灸  脓毒症  胃肠功能障碍  临床观察

Key words:  acupuncture  sepsis  gastrointestinal dysfunction  clinical observation

摘要:

[目的] 观察针灸改善脓毒症患者胃肠功能障碍的临床疗效。[方法] 将60例脓毒症胃肠功能障碍患者随机分为研究组和对照组，研究组脱落1例，剔除1例，对照组脱落1例，最终研究组28例，对照组29例。两组均给与脓毒症抗感染及脏器功能支持治疗，对照组在此治疗基础上加用口服胃肠动力药，研究组在此治疗基础上给与针灸治疗。两组均观察1周，观察指标包括治疗前后的急性生理与慢性健康评分Ⅱ（APACHEⅡ）评分、腹围、腹腔内压、肠鸣音及炎症反应指标（白细胞、C反应蛋白）。[结果] 两组治疗后APACHEⅡ评分均较治疗前降低（P<0.05），两组组间比较差异有统计学意义（P<0.01）。两组治疗前后腹围变化差异无统计学意义，两组腹腔内压变化在治疗前后差异均有统计学意义（P<0.05），两组组间比较差异有统计学意义（P<0.01）。两组肠鸣音在治疗前后差异均有统计学意义（P<0.05），两组组间比较差异有统计学意义（P<0.01）。两组白细胞与C反应蛋白在治疗前后差异均有统计学意义（P<0.05），但两组组间比较差异无统计学意义。[结论] 应用针灸治疗能改善脓毒症患者胃肠功能障碍的临床症状，增强胃肠动力。

Abstract:

[Objective] To observe the clinical effect of acupuncture on improving septic gastrointestinal dysfunction patients.[Methods] Sixty patients with septic gastrointestinal dysfunction were randomized divided into the research group (28 cases with 1 rejecting and 1 dropping) and the control group (29 cases with 1 dropping).On the base of sepsis anti-infection and organ function support treatment,the control group was also given oral prokinetic agents while the research group was also given acupuncture. Both groups were observed for 1 week.The APACHEⅡscore,abdominal circumference,intra-abdominal pressure,intestinal sounds and inflammation indicators(leukocyte,C-reactive protein) before and after treatment were observed.[Results] The change of APACHEⅡscore was statistically different in both groups before and after treatment(P<0.05),and the difference between the two groups was statistically significant(P<0.01). There was no significant difference in abdominal circumference between the two groups before and after treatment. The difference of intra-abdominal pressure between the two groups was statistically significant before and after treatment (P<0.05),and the difference between the two groups was statistically significant (P<0.01).The differences of intestinal sounds were statistically significant in both groups before and after treatment(P<0.05),and difference between the two groups was statistically significant (P<0.01).The differences of leukocyte and C-reactive protein were statistically significant in both groups before and after treatment(P<0.05),but the difference between the two groups was not statistically significant.[Conclusion] Acupuncture can improve the symptoms of septic gastrointestinal dysfunction patients and enhance gastrointestinal motility.