| 摘要: |
| 微炎症状态普遍存在于维持性血液透析患者中，与动脉粥样硬化、营养不良、脂质代谢紊乱、贫血、感染、透析充分性等多种因素相关，是导致心血管事件的关键因素。文章以查阅文献的方式，就近年来单味中药及其提取物治疗血液透析微炎症状态的相关研究进行总结，主要包括冬虫夏草、金蝉花、黄芪、大黄、丹参、白芍总苷、青藤碱、氧化苦参碱、水飞蓟素、白藜芦醇等为代表的药物，并总结了其抗微炎症状态的活性成分及相应作用机制，以期为中医药防治维持性血液透析微炎症状态的深入研究及治疗提供参考。 |
| 关键词: 单味中药 中药提取物 维持性血液透析 微炎症状态 |
| DOI：10.11656/j.issn.1672-1519.2021.11.25 |
| 分类号:R284.2 |
| 基金项目:陕西省科学技术厅项目（2017SF-298）；西安市科技计划项目[2019114613YX001SF044（9）]。 |
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| Research progress of single Chinese medicine and its extracts in prevention and treatment of micro-inflammatory state in maintenance hemodialysis |
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YANG Shaoning1, SUN Qian1, LI Shanshan1, ZHOU Jinwen2, YU Xiaoyong2
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1.The First Clinical Medical College of Shaanxi University of Chinese Medicine, Xianyang 712046, China;2.Second Department of Nephrology, Shaanxi Provincial Hospital of Chinese Medicine, Xi'an 710003, China
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| Abstract: |
| Micro-inflammatory states are common in hemodialysis patients,related to atherosclerosis,malnutrition,lipid metabolism disorders,anemia,infection,sufficiency of dialysis,and are the key factors leading to cardiovascular events. This article summarizes the related researches on the treatment of micro-inflammatory state of hemodialysis by single Chinese medicine and its extract in recent years by consulting the literature. It mainly includes drugs such as cordyceps sinensis,golden isaria cicadae miquel,astragalus membranaceus,rhubarb,salvia miltiorrhiza,total glucosides of paeony,sinomenine,oxymatrine,silymarin,resveratrol,etc. And summarized the active ingredients and corresponding mechanism of action against micro-inflammatory state,it is expected to provide a reference for the in-depth research and treatment of micro-inflammatory state of maintenance hemodialysis in traditional Chinese medicine. |
| Key words: single Chinese medicine Chinese herbal extract maintenance hemodialysis micro-inflammation state |
