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| 组学技术在推拿学科中的应用与刍议 |
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李华南1,2, 张玮1,2, 马菲3, 包安1, 陈英英1, 王海腾1, 王建伍1, 董桦1, 王金贵1
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1.天津中医药大学第一附属医院推拿科, 国家中医针灸临床医学研究中心, 天津 300193;2.国家中医药管理局推拿手法生物效应三级实验室, 天津 300193;3.天津市中医药研究院附属医院科研处, 天津 300120
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| 摘要: |
| 组学技术是近年来逐渐发展形成的一整套检测分析方法，该方法基于高通量分析和检测技术用于基因表达、蛋白质组成及变化规律、代谢定量分析等现代生物研究。同时，组学技术的整体性、动态性的特点，与中医药的作用不谋而合，现已被广泛应用于中医临床各学科的研究。但针对推拿学科的组学相关研究尚处于初步探索阶段，文献报道还不是很多。文章将结合组学技术特点，围绕推拿学科相关研究展开综述，并为今后本学科关键科学问题中应用组学技术研究提出一些新的研究思路，以飧后者。 |
| 关键词: 组学技术 推拿学科 效应机制 |
| DOI：10.11656/j.issn.1672-1519.2022.10.21 |
| 分类号:R244.1 |
| 基金项目:国家自然科学基金项目(81873393);国家中医药管理局中医药传承与创新"百千万"人才工程(岐黄工程)岐黄学者(国中医药人教函[2021]203号);天津中医药大学第一附属医院拓新工程课题项目(院ZD202105);天津市131优秀人才培养项目。 |
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| Application and discussion of omics technology in massage discipline |
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LI Huanan1,2, ZHANG Wei1,2, MA Fei3, BAO An1, CHEN Yingying1, WANG Haiteng1, WANG Jianwu1, DONG Hua1, WANG Jingui1
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1.Department of Tuina, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China;2.Level 3 Laboratory of Biological Effects of Tuina Manipulation, National Administration of Traditional Chinese Medicine, Tianjin 300193, China;3.Research Office, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin 300120, China
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| Abstract: |
| Omics technology is a set of detection and analysis methods gradually developed in recent years.This method is based on high-throughput analysis and detection technology for modern biological research such as gene expression,protein composition and change rules,and metabolic quantitative analysis.At the same time,the overall and dynamic characteristics of omics technology coincide with the role of traditional Chinese medicine,and it has been widely used in the research of various clinical disciplines of traditional Chinese medicine.However,the omics-related research on the subject of massage is still in the preliminary exploratory stage,and there are not many literature reports.In this paper,combined with the technical characteristics of omics,it will summarize the related research of massage discipline,and put forward some new research ideas for the application of omics technology in the key scientific issues of this discipline in the future,so as to avoid the latter. |
| Key words: omics technology massage discipline effect mechanism |
