腹针联合九味镇心颗粒治疗广泛性焦虑心脾两虚证的临床观察

Clinical observation on abdominal acupuncture combined with Jiuwei Zhenxin Granule in the treatment of generalized anxiety with heart and spleen deficiency syndrome

关键词:  腹针  九味镇心颗粒  心脾两虚  广泛性焦虑

Key words:  abdominal acupuncture treatment  Jiuwei Zhenxin Granule  heart and spleen deficiency syndrome  generalized anxiety

摘要:

[目的] 采用腹针联合九味镇心颗粒的治疗方法，探究针药结合治疗广泛性焦虑心脾两虚证的临床疗效，为临床提供参考。[方法] 选取2020年8月—2022年12月衡水市第七人民医院门诊以及住院的102例广泛性焦虑心脾两虚证患者作为研究对象，随机分为治疗组和对照组，各51例，治疗组予口服九味镇心颗粒加用腹针治疗，对照组单纯予以九味镇心颗粒。疗程均为4周。评估其焦虑量表评分（HAMA）、抑郁量表评分（HAMD）、中医证候量表评分（TCMDS）、睡眠质量评分（PSQI）、生活质量评分（SF-36）、HAMA疗效、证候疗效。[结果] 治疗1周后，两组HAMA评分、HAMD评分、TCMDS评分、PSQI评分即开始下降，治疗2、4周后明显下降，且治疗组下降更显著（P<0.05）；治疗组SF-36评分高于对照组（P<0.05）；临床疗效对比显示，治疗组HAMA疗效（92.00%）、证候疗效的总有效率（90.00%）均高于对照组的HAMA疗效（76.00%）和证候疗效的总有效率（74.00%），组间对比有统计学差异（P<0.05）。[结论] 腹针联合九味镇心颗粒治疗广泛性焦虑心脾两虚证患者的HAMA疗效与证候疗效确切，可减轻患者的焦虑状态与临床症状，且能改善患者的睡眠与生活质量，有利于患者康复，值得推行。

Abstract:

[Objective] To observe the clinical efficacy of abdominal acupuncture combined with Jiuwei Zhenxin Granules in the treatment of generalized anxiety with heart and spleen deficiency sydrome，and to explore an effective treatment scheme，so as to provide reference for clinical practice and promote patients’ early recovery. [Methods] The 102 patients of generalized anxiety with heart and spleen deficiency syndrome treated in Hengshui Seventh People’s Hospital outpatient and inpatient department from August 2020 to December 2022 were selected. All patients were randomly divided into two groups. There were 51 cases in the control group and 51 cases in the experimental group. The control group was treated with Jiuwei Zhenxin Granules （6 g each time，3 times a day，washed with warm boiled water）. The experimental group was treated with abdominal acupuncture on the basis of Jiuwei Zhenxin Granules. The treatment course of the two groups was 4 weeks. The anxiety scale score（HAMA），depression scale score（HAMD），traditional Chinese medicine syndrome scale score （TCMDS），sleep quality score （PSQI），quality of life score （SF-36），HAMA efficacy and syndrome efficacy were evaluated. [Results] After 1 week of treatment，HAMA score，HAMD score，TCMDS score and PSQI score of the two groups began to decline，and the decrease was more obvious after 2 weeks and 4 weeks，but the decrease was more significant in the treatment group（P<0.05）. The SF-36 score of the treatment group was higher than that of the control group（P<0.05）. The total effective rate of HAMA in the experimental group （92.00%） was higher than that in the control group （76.00%，P<0.05）. The total effective rate of syndrome curative effect in the experimental group （90.00%） was higher than that in the control group （74.00%，P<0.05）. [Conclusion] Abdominal acupuncture combined with Jiuwei Zhenxin Granules has a definite effect on HAMA and symptoms in the treatment of generalized anxiety with heart and spleen deficiency syndrome. It can reduce patients’ anxiety symptoms and clinical symptoms，improve patients’ sleep quality and quality of life，and is conducive to patients’ rehabilitation. It is worth promoting.