| 摘要: |
| [目的] 分析天降血栓通丸口服联合针刺在治疗急性缺血性脑卒中（AIS）的临床疗效及安全性。[方法] 回顾性收集2021年1月—2022年1月医院脑病科收治的AIS患者的临床资料。根据患者治疗方式的不同分为对照组和观察组，其中对照组采用阿替普酶（rt-PA）静脉溶栓治疗，观察组在此基础上采用天降血栓通丸联合针刺治疗。对比两组患者的美国国立卫生研究院卒中量表（NIHSS）评分、改良Rankin量表（mRS）评分、巴塞尔指数（BI）评分、匹兹堡睡眠质量指数（PSQI）评分以及不良反应发生率的差异。[结果] 观察组的NIHSS评分和PSQI评分显著低于对照组，mRS评分和BI评分明显高于对照组。两组患者治疗总有效率具有统计学差异（P＜0.05），不良反应发生率差异无统计学意义（P＞0.05）。[结论] 天降血栓通丸口服联合针刺治疗可有效改善患者的临床症状，改善患者脑卒中后失眠状况，同时不会增加不良反应发生风险。 |
| 关键词: 天降血栓通丸 针刺疗法 急性缺血性脑卒中 临床疗效 安全性 |
| DOI：10.11656/j.issn.1672-1519.2023.09.12 |
| 分类号:R743.3 |
| 基金项目: |
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| Clinical study of Tianjiang Xueshuantong Pill combined with acupuncture in the treatment of acute ischemic stroke |
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LI Yinghong1, LIU Yangyang2, DAI Fang1
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1.Department of Encephalopathy, Tianjin Beichen Traditional Chinese Medical Hospital, Tianjin 300400, China;2.School of Acupuncture-Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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| Abstract: |
| [Objective] To analyze the clinical efficacy and safety of Tianjiang Xueshuantong Pill（TXP） combined with acupuncture in the treatment of acute ischemic stroke（AIS）. [Methods] Clinical data of AIS patients admitted to the department of encephalopathy of our hospital from January 2021 to January 2022 were retrospectively collected. According to different treatment methods，patients were divided into control group and observation group. The control group was treated with alteplase（rt-PA） intravenous thrombolytic therapy，and the observation group was treated with TXP combined with acupuncture. The differences of national institutes of health stroke scale（NIHSS） score，modified rankin scale（mRS） score，barthel index（BI） score，pittsburgh sleep quality index（PSQI），and incidence of adverse reactions were compared between the two groups. [Results] The NIHSS score and the PSQI score in the observation group were lower than those in the control group，the mRS score and BI score were significantly higher than those in the control group. The total effective rate was significantly different between the two groups（P＜0.05），while the incidence of adverse reactions was not significantly different between the two groups（P＞0.05）. [Conclusion] TXP orally combined with acupuncture can effectively relieve the clinical symptoms of patients，and improve the insomnia status of patients after stroke without increasing the risk of adverse reactions. |
| Key words: Tianjiang Xueshuantong Pill acupuncture acute ischemic stroke clinical efficacy security |
