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| 基于数据挖掘技术的肺结节常见证候诊断依据分析 |
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孙雪鸽1,2, 赵虎雷1,3, 焦莉3,4, 周淼3,4, 王中超3,4, 黄艳3,4, 蒋艳丽3,4, 刘元元3,4, 李建生1,2,3
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1.河南中医药大学第一附属医院呼吸科, 郑州 450000;2.河南中医药大学第一临床医学院, 郑州 450000;3.河南中医药大学呼吸疾病诊疗与新药研发省部共建协同创新中心, 河南省中医药防治呼吸病重点实验室, 郑州 450046;4.河南中医药大学第三附属医院, 郑州 450004
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| 摘要: |
| [目的] 初步确立肺结节常见证候诊断依据。[方法] 基于746份肺结节临床资料，采用关联规则结合贝叶斯网络数据挖掘技术，分析肺结节常见证候中关联较强的症状群及其对该证候诊断的贡献度。[结果] 各常见证候关系密切的症状群及其对证候的贡献度分别为：1） 肺气虚证：乏力＆神疲（0.22）；2）肺脾气虚证：咳嗽＆痰色白（0.27）、咳嗽＆气短（0.19）、舌苔白腻＆舌质淡（0.57）、舌质淡＆脉细弱（0.36）、乏力＆纳呆（0.14）；3）痰浊阻肺证：咳嗽＆痰色白（0.32）、胸闷＆气短（0.19）。瘀阻肺络证尚未得到关系密切的症状群。[结论] 基于症状群对常见证候的贡献度，初步确立诊断条件与依据，可为肺结节证候诊断标准的建立提供依据，对瘀阻肺络证有贡献度的症状群有待进一步研究。 |
| 关键词: 肺结节 常见证候 症状 贡献度 诊断依据 |
| DOI：10.11656/j.issn.1672-1519.2024.07.04 |
| 分类号:R563 |
| 基金项目:国家中医药领军人才支持计划—岐黄学者资助（国中医药人教函〔2018〕284号）；河南省卫生健康委国家中医临床研究基地科研专项（2021JDZY029）；河南省高等学校重点科研项目（21A360007）。 |
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| Analysis of common syndromes diagnosis basis of pulmonary nodules based on data mining |
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SUN Xuege1,2, ZHAO Hulei1,3, JIAO Li3,4, ZHOU Miao3,4, WANG Zhongchao3,4, HUANG Yan3,4, JIANG Yanli3,4, LIU Yuanyuan3,4, LI Jiansheng1,2,3
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1.Department of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China;2.The First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou 450000, China;3.Henan University of Chinese Medicine Respiratory Disease Diagnosis and Treatment and New Drug Research and Development Provincial and Ministry Co-built Collaborative Innovation Center, Henan Key Laboratory of Chinese Medicine for Respiratory Diseases, Zhengzhou 450046, China;4.Third Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450004, China
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| Abstract: |
| [Objective] To preliminarily establish the diagnosis basis for common syndromes of pulmonary nodules. [Methods] The correlation between symptoms and their contribution to common syndromes was analyzed using association rules combined with a Bayesian network based on the clinical data of 746 clinical data of pulmonary nodules. [Results] Among the common syndromes，the closely related symptom groups and their contribution to the syndrome were as follows：1）lung qi deficiency syndrome：fatigue & spiritual tiredness（0.22）；2） lung spleen qi deficiency syndrome：cough & white phlegm（0.27），cough & shortness of breath（0.19），white greasy tongue fur & thin tongue（0.57），thin tongue & fine weak pulse（0.36），fatigue & poor appetite（0.14）；3） phlegm turbid obstructing the lung syndrome：cough & white phlegm（0.32），chest tightness & shortness of breath（0.19）. The syndrome of stasis obstructing lung collateral has not yet obtained a closely related symptom group. Conclusion based on the contribution of symptom clusters to common syndromes，the preliminary establishment of diagnostic conditions and basis can provide an objective basis for the establishment of diagnostic criteria for pulmonary nodules syndromes. The symptom clusters that contribute to the stasis lung collateral syndrome need to be further studied. [Conclusion] Based on the correlated symptom clusters and their contribution to syndromes，the diagnostic basis for common syndromes of pulmonary nodules were formed，which can provide a basis for the establishment of diagnostic criteria for pulmonary nodule common syndromes. However，the symptom clusters that contribute to the stasis lung collateral syndrome need to be further studied. |
| Key words: pulmonary nodules common syndrome symptom contribution degree diagnosis basis |
