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帕金森病抑郁治肝的中西医契合点之探讨与应用
吴江莹1, 丁晶1, 许迎春1, 刘晓新2,3, 吴潇哲1, 郭睿婧1, 郑娜1, 田珍1, 黄迪1
1.天津市环湖医院中医科, 天津 300350;2.天津中医药大学第一附属医院针灸临床部, 天津 300381;3.国家中医针灸临床医学研究中心, 天津 300381
摘要:
帕金森病抑郁是帕金森病非运动症状中常见的症状,但该症状在临床中却未得到充分的认识和治疗。目前中西医尚缺乏根治的办法。文章从帕金森病抑郁的病机及其与肝脏相关的西医机制之间的密切关系,探讨共同治“肝”之契合点的理论与应用,以期为各位同道提供参考与借鉴。
关键词:  帕金森病抑郁  线粒体  肝细胞  疏肝解郁  还原型谷胱甘肽
DOI:10.11656/j.issn.1672-1519.2024.09.06
分类号:R742.5
基金项目:天津市卫生健康委员会中医经典传承高级人才研修项目(2021642);天津市卫生健康委员会资助项目(2023061);国家中医药管理局全国中医药创新骨干人才培训项目(2019128)
Discussion and application of the combination of traditional Chinese and Western medicine in treating liver in Parkinson’s depression disease
WU Jiangying1, DING Jing1, XU Yingchun1, LIU Xiaoxin2,3, WU Xiaozhe1, GUO Ruijing1, ZHENG Na1, TIAN Zhen1, HUANG Di1
1.Department of Traditional Chinese Medicine, Tianjin Huanhu Hospital, Tianjin 300350, China;2.Clinic Department of Acupuncture Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China;3.National Clinical Research Center for Chinese Medicine Acupuncture Moxibustion, Tianjin 300381, China
Abstract:
Parkinson disease depression is a common non-motor symptom of Parkinson disease,but it is underrecognized and undertreated in the clinic. At present,there is no radical cure for traditional Chinese and Western medicine. From the pathogenesis of Parkinson disease depression and the close relationship between it and modern medical mechanism related to liver,this paper discusses the theory and application of the joint point of treating “liver” together,in order to provide reference for fellow travelers.
Key words:  Parkinson disease depression  mitochondria  hepatocellular  soothing liver-qi stagnation  reduced glutathione
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