通督调神针法联合己酮可可碱对脑梗死偏瘫患者上肢运动功能和日常生活能力的影响

Effects of union of Tongdu Tiaoshen acupuncture and hexanone theobromine on upper limb motor function and daily living ability in patients with cerebral infarction hemiplegia

关键词:  脑梗死偏瘫  己酮可可碱  通督调神针法  上肢运动功能  日常生活能力

Key words:  cerebral infarction hemiplegia  hexanone theobromine  Tongdu Tiaoshen acupuncture  upper limb motor function  daily living ability

摘要:

[目的] 探讨通督调神针法联合己酮可可碱治疗脑梗死偏瘫的临床疗效。[方法] 选取120例脑梗死偏瘫患者，随机分为两组，西医组给予己酮可可碱治疗，针刺组给予通督调神针法联合己酮可可碱治疗，比较两组疗效。[结果] 针刺组总有效率为93.33%，高于西医组的80.00%（P<0.05）。治疗后，针刺组中医证候积分、美国国立卫生研究院卒中量表（NIHSS）评分均低于西医组（P<0.05），上肢Fugl-Meyer运动功能评定表（FMA）评分、上肢Wolf运动功能测试（WMFT）评分及Barthel指数量表（BI）评分均高于西医组（P<0.05）。治疗后，针刺组血清过氧化氢酶（CAT）、超氧化物歧化酶（SOD）、脑源性神经营养因子（BDNF）水平高于西医组（P<0.05），同型半胱氨酸（Hcy）水平低于西医组（P<0.05）。治疗前后，两组患者的凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、凝血酶时间（TT）及纤维蛋白原（FIB）水平组内及组间比较差异均无统计学意义（P>0.05）。[结论] 采用通督调神针法联合己酮可可碱治疗脑梗死偏瘫具有显著疗效，可提高上肢运动功能及日常生活能力。

Abstract:

[Objective] To explore the clinical therapeutic effect of union of Tongdu Tiaoshen acupuncture and hexanone theobromine on cerebral infarction hemiplegia. [Methods] Totally 120 patients with cerebral infarction hemiplegia were stochastically divided into two groups. The Western drug group was injected with hexanone theobromine，while the acupuncture group adopted union of Tongdu Tiaoshen acupuncture and hexanone theobromine. The therapeutic effects were compared. [Results] The total effective rate in the acupuncture group was 93.33%，significantly higher than the 80.00% in the Western drug group（P<0.05）. After therapy，the acupuncture group had lower scores in Chinese medicine syndrome and the National Institutes of Health Stroke Scale（NIHSS，P<0.05），and higher scores in the upper limb Fugl-Meyer Motor Function Assessment（FMA），upper limb Wolf Motor Function Test （WMFT），and Barthel Index（BI）than the Western drug group（P<0.05）. After therapy，the acupuncture group had higher serum catalase（CAT），superoxide dismutase（SOD），and brain-derived neurotrophic factor（BDNF），P<0.05，and lower homocysteine（Hcy） than the Western drug group（P<0.05）. There were no statistically significant differences in prothrombin time（PT），activated partial thromboplastin time（APTT），thrombin time（TT），and fibrinogen（FIB）levels between groups or within groups before and after treatment（P>0.05）. [Conclusion] The union of Tongdu Tiaoshen acupuncture and hexanone theobromine has prominent therapeutic effects on cerebral infarction hemiplegia，and it can improve upper limb motor function and daily living ability.