摘要: |
[目的]探讨肺气虚大鼠血、尿中β2-微球蛋白的变化。[方法]采用熏烟加气管滴加脂多糖造肺气虚模型,用放射免疫方法检查大鼠血、尿中的β2-微球蛋白。[结果]经熏烟后的肺气虚组大鼠血、尿中β2-微球蛋白较正常对照组有明显改变。[结论]造模后肺气虚组大鼠的肾脏受到—定程度的损害,从实验方面证明了中医肺病及肾的理论。 |
关键词: 肺气虚 肺脏 β2-微球蛋白 |
DOI:10.11656/j.issn.1673-9043.2009.02.10 |
分类号: |
基金项目:* 山东省卫生系统高层次人才1020工程资助项目;山东省科技攻关基金资助项目(Y2006C113) |
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Study on Blood and Urine β2-microglobulin in Rats with Deficiency of Lung Qi |
ZHANG Wei,LIN Li,ZHAO Yun-yang
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The Affiliated Hospital of Shandong University of TCM, Jinan 250011, China
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Abstract: |
[Objective] To explore the change of blood and urine β2-microglobulin in rats with deficiency of lung Qi.[Methods] The model of lung-Qi deficiency was established by using hypatmism and dropwising lipopolysaccharide (LPS) into windpipe and the blood and urine β2-microglobulin was determined by using radio-immunity method.[Results] There was obvious change in blood and urine β2-microglobulin after the hypatmism in rats with deficiency of lung Qi.[Conclusion] There is a certain kidney injury in rats with deficiency of lung Qi.This study may prove the TCM theory of that the lung diseases may affect the kidney. |
Key words: deficiency of lung Qi lung disease β2-microglobulin |