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| 疏肝导浊方药治疗非酒精性脂肪肝的临床研究 |
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王威1, 李智2, 陆怡2, 江海涛3, 张俊华4, 史红4, 胡利民4, 方文岩5, 顾志敏1, 杨林1, 刘友刚1, 王超1, 田维1
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1.天津中医药大学 300193;2.天津市和平区中医医院 300158;3.天津中医药大学第二附属医院 300150;4.天津市中医药研究中心 300022;5.天津中医药大学第一附属医院 300193
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| 摘要: |
| [目的]观察疏肝导浊方药对脂肪肝患者的临床症状、脂质代谢和肝、肾功能的影响。[方法]临床随机选取72例脂肪肝患者服用疏肝导浊方药3个月,服药前与服药后自身对照观察临床症状,进行药物有效率处理;服药前与服药后3个月的血糖(BG)、甘油三酯(TG)、胆固醇(TC)、谷丙转氨酶(ALT)、尿素氮(BUN)和肌酐(Cr)结果采用随机区组设计方差分析进行统计处理。[结果]疏肝导浊方药可以降低血清中BG、TG、TC和ALT的含量(P<0.01),对BUN和Cr的含量没有影响(P>0.05);服药前、后自身对照临床症状观察总有效率为67%。[结论]疏肝导浊方药可促进脂肪肝患者血糖血脂和ALT酶活性的降低,促进脂质代谢,恢复肝功能,治疗脂肪肝,并且在患者服药3个月中尚未发现肾脏损害。 |
| 关键词: 脂肪肝 疏肝导浊方药 胆固醇 甘油三酯 |
| DOI：10.11656/j.issn.1673-9043.2010.03.06 |
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| Treating Non-alcohol Fatty Liver with Shugan Daozhuo Prescription |
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WANG Wei,LI Zhi,LU Yi
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Tianjin University of TCM, Tianjin 300193, China
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| Abstract: |
| [Objective] To observe the effects of Shuogandaozhuo (Dispersing the stagnated liver QI and Reducing the turbid pathogen) medicine (SM) on patient with fatty liver,including clinic symptom,lipid metabolism and hepatic,nephric function．[Method] Seventy-two patient with fatty liver were randomly enrolled and treated with Shuogandaozhuo medicine for 3 months.Before and after treatment selfcomparisons were performed on the clinic symptom,BG,TG,TC,ALT,BUN,Cr.[Results] Shuogandaozhuo medicine could reduce the serum BG,TG,TC and ALT levels of patient with fatty liver (P<0.01).No effect was found on the content of BUN,Cr levels.[Conclusion] SM can promote the reducing of blood glucose and lipid levels and serum ALT activity. |
| Key words: fatty liver Shugandaozhuo Medicine cholesterol triglyceride |
