肠内营养结合加味四君子汤对肠梗阻术后患者肠功能的影响

Effect of enteral nutrition with decoction of Jiawei Four Mild Drugs on intestines function of patients with postoperative intestinal obstruction

关键词:  肠梗阻  肠内营养  加味四君子汤  营养状况  肠黏膜屏障功能

Key words:  intestinal obstruction  enteral nutrition  Jiawei Four Mild Drugs Decoction  nutritional status  Intestinal mucosal barrier function

摘要:

[目的]观察肠梗阻手术后早期肠内营养、肠内营养结合加味四君子汤对患者营养状况的改善以及对肠黏膜屏障功能的影响。[方法]将60例已经实行手术治疗的肠梗阻患者随机分为肠内营养(EN)组,中药(EN+加味四君子汤)组。术后给予营养支持,中药组同时给予加味四君子汤。检测患者术前、术后2d和术后8d的营养指标及血浆二胺氧化酶(DAO)活性及血浆D-乳酸水平,比较营养状况的改善及肠道功能恢复情况。[结果]术后第2天两组患者的营养状况较术前降低,经过不同方式的营养支持及中药治疗后,术后第8天两组患者的营养状况及肠黏膜屏障功能均较术前明显改善,存在统计学差异。[结论]肠梗阻患者手术后早期行肠内营养及中药支持,能有效改善患者营养状况和肠黏膜屏障功能,促进胃肠道功能恢复。

Abstract:

[Objection] To observe the effect of Intestinal mucosal barrier function in early enteral nutrition,early enteral nutrition with Jiawei Four Mild Drugs Decoction on postoperation intestinal obstruction.[Methods] The sixty patients suffering from intestinal obstruction after surgical operation were randomly divided into the EN group (n=30,treated with EN after operation) and the traditional medicine group (n=30,treated with Jiawei Four Mild Drugs Decoction with EN).Preventive measures for infections of the patients were taken by both groups.Since the 2nd postoperative day Neutrinos (r) was infused,and the traditional medicine group was given Jia Wei Si Jun Zi Decoction.Nutrition index,DAO Activities,level of plasma D-lactate were detecting on pre-operation,the 2nd postoperative day,the 8th postoperative day.bowel sound was taken at different time.The gut funciton was evaluated,Comparison of the nutritional status of patients and recovery of gut function.[Results] The nutritional status of both groups were worse than pre-operation on 1st postoperative day,after diffent nutrition support,the nutritional status and Intestinal mucosal barrier function of both groups were improved significantly.It showed statistical difference.And the traditional medicine group was better than EN group.[Conclusion] Intestinal mucosal barrier function and the nutritional status were improved effectly when the EN and traditional medicine were given.Gut function recovery was prompted.