| 摘要: |
| [目的]研究川续断(Dipsacus asperoides)的化学成分。[方法]采用溶剂提取、重结晶和硅胶色谱方法分离纯化,根据氢谱、碳谱以及与对照品共薄层色谱鉴定化合物的结构。[结果]从川续断的70%乙醇提取物中分离鉴定了10个化合物:β-谷甾醇(1),蔗糖(2),胡萝卜苷(3),乙二醇(4),3-O-α-L-吡喃阿拉伯糖-常春藤皂苷元(5),3-O-α-L-吡喃阿拉伯糖-齐墩果酸-28-O-β-D-吡喃葡萄糖-(1→6)-β-D-吡喃葡萄糖苷(6),木通皂苷D(7),3-O-α-L-吡喃阿拉伯糖-常春藤皂苷元-28-O-β-D-吡喃葡萄糖苷(8),马钱子苷(9),TriplostosideA(10)。[结论]化合物(4)为首次在川续断属植物中分离得到。 |
| 关键词: 川续断 三萜皂苷 常春藤皂苷元 |
| DOI：10.11656/j.issn.1673-9043.2010.03.14 |
| 分类号: |
| 基金项目:*科技部国际合作项目(2008DFB30070);天津市重点项目(06TXTJJCB600) |
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| Studies on chemical constituents in dipsacus asperoides |
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WU Shuai, LIU Er-wei, ZHANG Yi
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The Key Laboratory for Prescription of National Educational Ministry of China, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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| Abstract: |
| [Objection] To study the chemical constituents in Dipsacus asperoides.[Methods] The compounds were separated and purified by solvent extraction,recrystallization and chromatography on silica gel and polyamide column.Their structures were elucidated on the basis of 1H-NMR,13C-NMR,and co-TLC with authentic samples.[Results] Ten compounds were identified:β-sitosterol (1) ,Sucrose (2) ,Daucosterol (3) ,Ethylene glycol (4) ,Cauloside A (5) ,3-O-α-L-arabinopyranosyl-Oleanolicacid-28β-D-glucopyranosyl- (1→6) -β-D-glucopyranoside (6) ,Akebiasaponin D (7) ,HN saponin F (8) ,Loganin (9) ,Triplostoside A (10).[Conclusion] Compound 4 was obtained from the title plant for the first time. |
| Key words: Dipsacus asperoides triterpenoid saponin hederagenin |
