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川芎天麻汤对小鼠的镇痛及抗疲劳作用
付彦君1, 李新2
1.辽宁中医药大学基础医学院, 沈阳 110847;2.辽宁中医药大学信息工程学院, 沈阳 110847
摘要:
[目的] 观察川芎天麻汤对小鼠镇痛和抗疲劳作用的影响. [方法] 用醋酸扭体法和热板法观察川芎天麻汤对小鼠的镇痛作用. 用游泳实验观察川芎天麻汤对小鼠抗疲劳能力的影响. [结果] 川芎天麻汤可显着减少小鼠腹腔注射醋酸引起的扭体反应次数;显着延长小鼠热痛阈值;显着延长小鼠的游泳时间. [结论] 川芎天麻汤对小鼠实验性疼痛有镇痛作用,可增强小鼠的抗疲劳能力.
关键词:  川芎  天麻  镇痛  抗疲劳
DOI:10.11656/j.issn.1673-9043.2014.01.09
分类号:
基金项目:
Analgesic and anti-fatigue effect of Chuanqiong Tianma decoction in mice
FU Yan-jun1, LI Xin2
1.School of Basic Medicine Science, Liaoning University of TCM, Shenyang 110847, China;2.Institute of Information Engineering, Liaonig University of TCM, Shenyang 110847, China
Abstract:
[Objective] To observe the analgesic and anti-fatigue effect of Chuanqiong Tianma decoction(RGD) in mice. [Methods] The analgesic and anti-fatigue effect were tested by acetic acid twisting method and hot-plate method in mice. [Results] The twisting times was significantly reduced and the response latency in hot-plate test was significantly prolonged by RGD. [Conclusion] RGD has analgesic and anti-fatigue effect in mice.
Key words:  Rhizoma ligustici wallichii  Gastrodia elata  analgesic effect  anti-fatigue effect
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