| 摘要: |
| [目的] 观察补肾调冲方与脱氢表雄酮（DHEA）治疗卵巢储备功能降低（DOR）所致不孕症患者的临床疗效。[方法] 将60 例DOR所致不孕症的患者随机分为3 组，即补肾调冲方组、DHEA 组、安慰剂组，均治疗3 个月经周期。[结果] 补肾调冲方可显著改善DOR患者临床症状、血清性激素水平及四清抗苗勒氏管激素（AMH）、抑制素B（INHB）值，增加卵巢窦卵泡数（AFC），提高卵巢储备功能，其疗效优于DHEA，差异有统计学意义（P<0.05）。[结论] 补肾调冲方在治疗因DOR所导致不孕症方面较DHEA疗效显著，且未发现有明显的毒副作用和不良反应，值得临床推广应用。 |
| 关键词: 不孕症 卵巢储备功能降低 补肾调冲方 脱氢表雄酮 |
| DOI： |
| 分类号: |
| 基金项目:国家自然科学基金（81273791）。 |
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| Effect of Bushen Tiaochong recipe and dehydroepiandrosterone for infertility women with diminished ovarian reserve |
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XIA Tian1, ZHAO L-ying2, WANG Ba-juan1, FU Yu1, MA Ru-hong1
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1.Collaborative Innovation Center of Reproductive Disease with Combination of TCM and Western Medicine, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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| Abstract: |
| [Objective] To evaluate the effect of Bushen Tiaochong recipe(BTR) and dehydroepiandrosterone(DHEA) for infertility women with diminished ovarian reserve. [Methods] Sixty infertility women caused by DORassigned into 3 groups randomized, interventions of which were BTR, DHEA, and placebo respectively. All enrolled women would be treated for 3 menstrual cycles. [Results] Women's clinical symptoms, serum hormone level, serum AMH and INHB concentration and AFC number were all improved in BTR and DHEA groups, but former was even better than latter. [Conclusion] The effect of BTR for infertility women with DOR is more remarkable than DHEA, and BTR is safer, which should be apply in clinical practice. |
| Key words: infertility diminished ovarian reserve Bushen Tiaochong recipe dehydroepiandrosterone |
