黄连温胆汤加减与舒乐安定治疗失眠的临床观察

Clinical observation of modified Huanglian Wendan decoction and Surazepam treating on insomnia

关键词:  失眠  黄连温胆汤  痰热内扰型  临床观察

Key words:  insomnia  Huanglian Wendan decoction  syndrome of phlegm-heat internal disturbance  clinical observation

摘要:

[目的] 比较黄连温胆汤加减与舒乐安定治疗痰热内扰型失眠的临床疗效。[方法] 选取符合纳入标准的原发性失眠患者120例, 随机分为治疗组和对照组, 治疗组每日口服黄连温胆汤1剂, 对照组每日于睡前口服舒乐安定2 mg, 10 d为1个疗程, 2个疗程后评估疗效, 统计黄连温胆汤加减治疗失眠的总有效率。[结果] 治疗组总有效率为 74.1%, 对照组总有效率为 82.7%, 两组间差异无统计学意义, 但治疗组不良反应的例数少于对照组。[结论] 黄连温胆汤加减治疗痰热内扰型失眠在临床疗效方面和舒乐安定相当, 且复发率低, 不良反应少。

Abstract:

[Objective] To investigate the clinical efficacy of Huanglian Wendan decoction and Surazepam in the treatment of insomnia of internal disturbance of phlegm-heat.[Methods] We selected the 120 cases of insomnia patients which consistent with selected standard. The patients were randomly divided into the treatment group and the control group. The treatment group was given Huanglian Wendan decoction, and the control group was taken Surazepam 2 mg before sleeping. 10 d for a course of observation. After two courses of treatment assessment of curative effect, and make statistic of the effective rate of Huanglian Wendan decoction in the treatment of insomnia.[Results] The total effective rate of test group was 74.07%, and the control group only was 82.69%, with no statistically significant difference between the two groups. But the side effect of treatment group patients was less then the control group. [Conclusion] Huanglian Wendan decoction has an obvious effect in the treatment of insomnia of internal disturbance of phlegm-heat and low recurrence rate, less side effects.